PMID: 1201885Dec 1, 1975Paper

Ultrastructure of keloid: an unusual incident involving lepromatous leprosy

International Journal of Dermatology
R F Dyer, C D Enna

Abstract

A patient with lepromatous leprosy developed keloids on the dorsum of both arms in response to ulcerations due to acute erythema nodosum leprosum reactions. Electron microscopic examination of the keloidal dermis showed a morphology indicative of increased production of normal collagen fibrils. The greatest cellular changes from normal were in fibroblasts which were enlarged due to increased amounts of rough endoplasmic reticulum and extensive Golgi complexes. Nuclear folds were also evident in these fibroblasts. Some cells, considered to be fibroblasts, were filled with cytoplasmic filaments and contained bizarre shaped nuclei. Mast cells, blood vessels and nerve processes were also present.

References

Oct 1, 1972·The Journal of Investigative Dermatology·H A LinaresD L Larson
Jan 1, 1974·Human Pathology·G B RyanG Majno
Feb 1, 1974·Plastic and Reconstructive Surgery·L D KetchumF W Masters
May 1, 1974·The Anatomical Record·C W Kischer
Aug 1, 1974·The Anatomical Record·A R Ten Cate, E Freeman
Jul 1, 1970·Southern Medical Journal·E E PeacockW C Trier

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Citations

Jan 1, 1993·Eye·N M Shoukrey, K F Tabbara
May 1, 1985·Acta Pathologica Japonica·H KiryuM Enjoji
Jan 1, 1981·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·Z Jurukova, C Milenkov
Jul 1, 1980·Journal of the American Academy of Dermatology·W D JamesR B Odom
Feb 1, 1984·The Journal of Surgical Research·K A PasykG W Cherry
Feb 14, 2002·Journal of Cutaneous Pathology·Nandan V KamathNancy S House
Feb 1, 1977·The Anatomical Record·R F Dyer, R D Peppler

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