PMID: 2492690Jan 1, 1989Paper

Ultrastructure of metaplastic ciliated cells in human stomach

Virchows Archiv. A, Pathological Anatomy and Histopathology
C TorikataH Kawakita

Abstract

Intestinal metaplasia of the gastric mucosa occurs commonly in aged Japanese patients and has been discussed in relation to the high incidence of gastric cancer in Japanese. Ciliated cells in the gastric mucosa have frequently been found in association with intestinal metaplasia in the pyloric gland and rarely in the cardiac gland in many Japanese patients, and exceptionally in one Chinese and in one Swedish patient. Electron microscopic examination of 12 Japanese patients has revealed that these structures are not metaplastic stereocilia, but true cilia. Ciliated cells have been found in the basal part of the gastric glands and never in the surface epithelium. The fine structure of the gastric cilia was almost the same as that of normal respiratory cilia. However, in the gastric cilia, most dynein arms were inconspicuous even after tannic acid fixation, indicating that ciliary beating of the gastric cilia is problematic. Abnormal cilia and basal bodies also were found. Ciliated cells have always occurred in association with intestinal metaplasia, therefore this phenomenon might be a type of metaplasia and is named "ciliated metaplasia" of the gastric mucosa.

References

Aug 1, 1977·Beiträge Zur Pathologie·K YamashiroT Nagayo
Jul 1, 1976·Archivum Histologicum Japonicum = Nihon Soshikigaku Kiroku·T Okuda, T Ogata
Feb 1, 1990·Acta Pathologica Japonica·C TorikataH Kawakita
Aug 1, 1986·Pathology, Research and Practice·C A Rubio, A Serck-Hanssen
Feb 1, 1985·Bulletin of Environmental Contamination and Toxicology·J B FerrarioJ L Laseter
May 1, 1972·The Journal of Cell Biology·N B Gilula, P Satir
Jan 1, 1973·The Journal of Pathology·R L Ailsby, F N Ghadially
Nov 1, 1973·The Journal of Cell Biology·L G TilneyD H Snyder

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Citations

Jan 1, 1989·Virchows Archiv. A, Pathological Anatomy and Histopathology·C Torikata, M Mukai
Jan 1, 1990·Virchows Archiv. A, Pathological Anatomy and Histopathology·C Torikata, M Mukai
Jan 1, 1991·Virchows Archiv. A, Pathological Anatomy and Histopathology·Y MoritaS Makihara
Jan 13, 2005·The American Journal of Surgical Pathology·Kaiyo TakuboKen-Ichi Mafune
Jun 1, 1989·Acta Pathologica Japonica·C TorikataH Kawakita
Feb 1, 1990·Acta Pathologica Japonica·C TorikataH Kawakita
Oct 15, 2013·Annals of the New York Academy of Sciences·Henry D AppelmanAndrew M Bellizzi
Oct 1, 1993·Human Pathology·W Y ChanS C Chung
Jan 6, 2021·Genesis : the Journal of Genetics and Development·Peter Walentek

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