Ultraviolet exposure influences laser-induced wounds, scars, and hyperpigmentation: a murine study

Plastic and Reconstructive Surgery
M HaedersdalH C Wulf

Abstract

Laser therapy is today considered the treatment of choice for vascular skin lesions, which commonly are located on the face and, therefore, frequently are exposed to sunlight. The purpose of this study was to examine whether preoperative and postoperative ultraviolet irradiation influences the development of laser-induced side effects. We laser-treated hairless mice with a copper vapor laser; three different intensities were used at a constant pulse duration. Simulated solar ultraviolet radiation was administered either before the laser treatment (3 consecutive days, daily doses of 2.48 J/cm2) or after the laser treatment (four times weekly in 4 weeks, daily doses of 1.66 J/cm2). Laser-induced wounds, scars, and hyperpigmentation were evaluated by macroscopic, histologic, and biochemical examinations. Preoperative ultraviolet exposure enlarged the laser-induced wounds and the areas with texture change at some of the laser intensities used. However, the most pronounced effect was seen for postoperative ultraviolet-irradiated mice. These mice developed, at some of the laser intensities, a higher incidence of bulging infiltration as well as higher degrees of fibrosis and hyperpigmentation, thus developing a poor cosmetic appearanc...Continue Reading

References

Oct 1, 1991·British Journal of Plastic Surgery·S K DasS F Davidson
Apr 1, 1991·British Journal of Plastic Surgery·S F DavidsonS K Das
Jan 1, 1990·The Journal of Surgical Research·I NordbackM Järvinen
Jul 1, 1981·The Journal of Investigative Dermatology·R R Anderson, J A Parrish
Feb 1, 1995·Photodermatology, Photoimmunology & Photomedicine·A B HansenH C Wulf
Apr 1, 1993·Burns : Journal of the International Society for Burn Injuries·M HaedersdalH C Wulf
Apr 1, 1993·The Journal of Dermatologic Surgery and Oncology·S M DinehartS Flock
Jul 1, 1995·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·M R KaiserB A Mertz

❮ Previous
Next ❯

Citations

May 15, 2007·Annals of Vascular Surgery·Anthony Mekako, Ian Chetter
Aug 4, 2009·Journal of the European Academy of Dermatology and Venereology : JEADV·L W Idorn, M Haedersdal
Jun 4, 2014·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Stan MonstreyLuc Téot
Feb 11, 2005·Lasers in Surgery and Medicine·Lene HedelundThomas Poulsen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
J J BerganM P Goldman
Journal of Vascular and Interventional Radiology : JVIR
Robert J MinS E Zimmet
The Journal of Dermatologic Surgery and Oncology
R R Anderson
Journal of Vascular and Interventional Radiology : JVIR
R J MinM D Forrestal
© 2022 Meta ULC. All rights reserved