PMID: 8597858Sep 1, 1995Paper

Umbilical cord stricture and intrauterine fetal death

Pediatric Pathology & Laboratory Medicine : Journal of the Society for Pediatric Pathology, Affiliated with the International Paediatric Pathology Association
Y SunV Billson

Abstract

Umbilical cord stricture is an uncommon but distinctive condition associated with intrauterine fetal death. Although cases have been reported periodically since the last century, there has been considerable speculation as to whether the condition is real or a postmortem artifact. In the present study, 25 cases reported since 1925 are reviewed and 8 new cases are described. Clinically, a decrease in fetal movements is usually the only symptom during the second or third trimester of pregnancy and fetal death occurs soon after. The women's age, health, and previous history have shown no link with this condition, but a higher incidence is noted in twin pregnancies. Morphologically, most infants are macerated and an extremely narrow segment of umbilical cord is usually seen at the fetal end and rarely at the placental end or in multiple sites along the cord. Absence of Wharton's jelly, stenosis, or obliteration of cord vessels at the narrow segment and intravascular cord thrombosis are the major pathological features. The findings of this study support the view that the condition can cause fetal death and alerts both pathologists and clinicians to the important features identifying this cause of perinatal wastage.

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Citations

Jun 1, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·E Di NaroV D'Addario
Feb 4, 2005·Journal of Clinical Ultrasound : JCU·Fabio GhezziPeter Dürig
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Nov 14, 2008·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·José I RodríguezPablo Lapunzina
Jul 1, 2006·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Hong Qi PengEllen Kahn
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Jun 26, 2003·Archives of Pathology & Laboratory Medicine·Vivekanand SinghMeenal Singh

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