UMC, another Cromer-related blood group antigen.

Transfusion
G L DanielsM Ikuta

Abstract

An antibody found in the serum of a Japanese blood donor detects a new high-frequency red cell antigen named UMC. UMC is absent from Inab phenotype cells, weakly expressed on Dr(a-) cells, and destroyed by alpha-chymotrypsin but not trypsin treatment of red cells. UMC is, therefore, a Cromer-related antigen. Immunoblotting with anti-UMC showed that UMC antigen, in common with other Cromer-related antigens, is carried on a red cell surface glycoprotein with an apparent molecular weight of 70,000, which presumably is the complement regulatory protein decay-accelerating factor.

Citations

Jan 1, 1995·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·M J Telen
Aug 3, 2004·Transfusion Medicine·J BanksM E Reid
Apr 5, 2003·Transfusion·Jill R StorryMarion E Reid
Aug 30, 2007·Transfusion·Kim Hue-RoyeMarion E Reid
Jan 1, 1995·Transfusion Medicine Reviews·M J Telen

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