Unaltered intrinsic functional brain architecture in young women with primary dysmenorrhea

Scientific Reports
Lin-Chien LeeJen-Chuen Hsieh

Abstract

Primary dysmenorrhea (PDM), painful menstruation without organic causes, is the most prevalent gynecological problem in women of reproductive age. Dysmenorrhea later in life often co-occurs with many chronic functional pain disorders, and chronic functional pain disorders exhibit altered large-scale connectedness between distributed brain regions. It is unknown whether the young PDM females exhibit alterations in the global and local connectivity properties of brain functional networks. Fifty-seven otherwise healthy young PDM females and 62 age- and education-matched control females participated in the present resting-state functional magnetic resonance imaging study. We used graph theoretical network analysis to investigate the global and regional network metrics and modular structure of the resting-state brain functional networks in young PDM females. The functional network was constructed by the interregional functional connectivity among parcellated brain regions. The global and regional network metrics and modular structure of the resting-state brain functional networks were not altered in young PDM females at our detection threshold (medium to large effect size differences [Cohen's d ≥ 0.52]). It is plausible that the abs...Continue Reading

References

Jul 1, 1990·British Journal of Obstetrics and Gynaecology·G SundellB Andersch
Jun 12, 1998·Nature·D J Watts, S H Strogatz
Nov 3, 2001·Physical Review Letters·V Latora, M Marchiori
Dec 13, 2003·Journal of Women's Health·Karen BarnardLisa M Sullivan
Apr 28, 2004·Pain·A Vania ApkarianDante R Chialvo
Jul 13, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·M E J Newman
Aug 21, 2004·Neuroinformatics·Olaf Sporns, Jonathan D Zwi
Dec 17, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·M E J Newman
Aug 11, 2005·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Jukka-Pekka OnnelaKimmo Kaski
Feb 3, 2006·Cerebral Cortex·C J StamPh Scheltens
Aug 1, 2006·Schizophrenia Research·Sifis MicheloyannisMichael Zervakis
Feb 6, 2007·PLoS Computational Biology·Sophie Achard, Ed Bullmore
Nov 10, 2007·Proceedings of the National Academy of Sciences of the United States of America·Hanbing LuElliot A Stein
Feb 27, 2008·Brain : a Journal of Neurology·Yong LiuTianzi Jiang
May 2, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Yong HeAlan Evans
Jun 28, 2008·PLoS Computational Biology·Kaustubh SupekarMichael D Greicius
Sep 12, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Danielle S BassettAndreas Meyer-Lindenberg
Feb 4, 2009·Proceedings of the National Academy of Sciences of the United States of America·C J HoneyP Hagmann
Feb 5, 2009·Nature Reviews. Neuroscience·Ed Bullmore, Olaf Sporns
Feb 25, 2009·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Lorah D DornElizabeth J Susman
Apr 14, 2009·NeuroImage·Cheng-Hao TuJen-Chuen Hsieh
Jun 6, 2009·Current Opinion in Neurology·Danielle S Bassett, Edward T Bullmore
Oct 13, 2009·NeuroImage·Mikail Rubinov, Olaf Sporns
Dec 2, 2009·Frontiers in Neuroinformatics·David MeunierEdward T Bullmore
Dec 29, 2009·NeuroImage·Andrew ZaleskyEdward T Bullmore
May 18, 2010·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Martijn P van den Heuvel, Hilleke E Hulshoff Pol
May 28, 2010·Arthritis and Rheumatism·Vitaly NapadowRichard E Harris
Jun 18, 2010·Brain Research Reviews·Eric A MoultonDavid Borsook
Jul 16, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mary-Ellen LynallEd Bullmore
Aug 14, 2010·Pain·Cheng-Hao TuJen-Chuen Hsieh
Sep 21, 2010·NeuroImage·Danielle S BassettScott T Grafton
Oct 30, 2010·Frontiers in Systems Neuroscience·Aaron F Alexander-BlochEdward T Bullmore
Jan 6, 2011·Frontiers in Neuroinformatics·Pablo BalenzuelaDante R Chialvo
Feb 19, 2011·Nature Reviews. Neuroscience·Alexander J ShackmanRichard J Davidson
Aug 4, 2011·NeuroImage·Koene R A Van DijkRandy L Buckner
Oct 1, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Marwan N BalikiA Vania Apkarian
Oct 5, 2011·Cerebral Cortex·Xi-Nian ZuoMichael P Milham
Jan 3, 2012·Psychosomatic Medicine·Ignacio CifrePedro Montoya

❮ Previous
Next ❯

Methods Mentioned

BETA
pregnancy test

Software Mentioned

Brain Connectivity Toolbox
MATLAB
SPSS
R
SPSS Statistics
Power
Statistical Parametric Mapping

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.