PMID: 2492489Jan 1, 1989Paper

Unambiguous typing for HLA-DQ TA10 and 2B3 specificities using specific oligonucleotide probes

Human Immunology
M J KenterM J Giphart

Abstract

Oligonucleotide probes specific for the serologically defined TA10 and 2B3 specificities were selected based on a comparison of the available HLA-DQ beta sequences. Panel and family segregation studies confirm a complete correlation between the reactivities of the selected probes and the TA10/IIB3 antibodies. The Glu residue at position 45 of the HLA-DQ beta chain is specific for the TA10 determinants, and a DQ beta Gly-Val-Tyr sequence is found at position 45-47 for all 2B3-positive DQ beta chains.

References

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Citations

Jan 4, 1993·Journal of Immunological Methods·B SánchezA Núñez-Roldán
Jun 1, 1991·Human Immunology·J MolkentinL A Baxter-Lowe
Dec 1, 1989·Clinical Immunology and Immunopathology·R Wassmuth, A Lernmark
Oct 1, 1990·Tissue Antigens·D P SingalS K Sood
Sep 1, 1989·Immunology Today·S G Marsh, J G Bodmer

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