Unbuffered and buffered supply chains in human metabolism

Journal of Biological Physics
Dirk Langemann, Marcel Rehberg


The investigation of very complex dynamical systems like the human metabolism requires the comprehension of important subsystems. The present paper deals with energy supply chains as subsystems of the metabolism on the molecular, cellular, and individual levels. We form a mathematical model of ordinary differential equations and we show fundamental properties by Fourier techniques. The results are supported by a transition from a system of ordinary differential equations to a partial differential equation, namely, a transport equation. In particular, the behavior of supply chains with dominant pull components is discussed. A special focus lies on the role of buffer compartments.


Apr 15, 1996·Archives of Biochemistry and Biophysics·N ErcanF Q Nuttall
Feb 13, 1999·Science·Pierre J MagistrettiR G Shulman
Nov 23, 2000·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·M SasvariD E Wolf
Jan 15, 1953·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·G C KENNEDY
Jul 2, 1953·The New England Journal of Medicine·J MAYER
Jun 3, 2004·Neuroscience and Biobehavioral Reviews·A PetersH L Fehm
Jul 13, 2006·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Leif HertzGerald A Dienel
Jan 6, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Erin Keen-Rhinehart, Timothy J Bartness
Feb 3, 2007·Progress in Neurobiology·Achim PetersH L Fehm
Apr 27, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Achim PetersH L Fehm
Jul 31, 2007·Glia·Luc PellerinPierre J Magistretti
Jul 31, 2007·Glia·Angus M Brown, Bruce R Ransom
Nov 6, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·K M OltmannsLuc Pellerin
Jan 24, 2009·Trends in Neurosciences·Raymond C KoehlerDavid R Harder
Aug 12, 2009·Journal of Biological Physics·Dirk Langemann, A Peters


Oct 4, 2011·Journal of Theoretical Biology·B GöbelDirk Langemann
Sep 7, 2014·Journal of Theoretical Biology·Louisa RoseliusRichard Münch

Related Concepts

Body Fluid Compartments

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.