Uncinate fasciculus white matter connectivity related to impaired social perception and cross-sectional and longitudinal symptoms in patients with schizophrenia spectrum psychosis.

Neuroscience Letters
Sra JungSang-Hyuk Lee

Abstract

Dysfunctional social-emotional perception in patients with schizophrenia can result in adverse clinical symptoms and poorer long-term outcomes. The white matter tracts that interact among a number of brain regions have an important role to play. However, few neuroimaging studies focus on the effects of white matter connectivity on social-emotional perception in schizophrenia and its impact on patients' clinical symptoms and long-term outcomes. Forty-one patients with schizophrenia spectrum psychosis and 42 healthy controls underwent structural magnetic resonance imaging. The white matter fractional anisotropy values of the emotion recognition areas, the bilateral anterior thalamic radiation, inferior longitudinal fasciculus, cingulum bundle, superior longitudinal fasciculus, and uncinate fasciculus were compared between patients with schizophrenia spectrum psychosis and healthy controls. Social-emotional perception levels and symptom severity at baseline and after 1 year were examined. A group analysis showed that white matter connectivity was significantly lower in the bilateral anterior thalamic radiation, cingulum bundle, right inferior longitudinal fasciculus, and uncinate fasciculus of patients with schizophrenia spectrum ...Continue Reading

References

Nov 1, 1990·Psychiatry·G SullivanJ Mintz
Jan 1, 1987·Schizophrenia Bulletin·S R KayL A Opler
Oct 31, 1998·Psychiatry Research·G H IhnenJ Martin
Dec 1, 2001·Schizophrenia Research·Rosemary ToomeyMichael F Green
Mar 5, 2002·Psychiatric Services : a Journal of the American Psychiatric Association·Michael B First, Harold Alan Pincus
Sep 7, 2002·Clinical Psychology Review·Jane EdwardsPhilippa E Pattison
Oct 16, 2002·Psychiatry Research·Christine Hooker, Sohee Park
May 14, 2003·Archives of General Psychiatry·Kenneth L DavisVahram Haroutunian
Apr 21, 2006·NeuroImage·Stephen M SmithTimothy E J Behrens
Nov 8, 2006·Psychiatry Research·Eric Brunet-Gouet, Jean Decety
Mar 3, 2007·The American Journal of Psychiatry·Sukhwinder S ShergillPhilip McGuire
Mar 14, 2007·International Review of Neurobiology·Olivier GuillinMarc Laruelle
Jun 15, 2007·Schizophrenia Research·Amelia L NelsonMichael R Basso
Sep 16, 2009·Psychological Medicine·C González-BlanchB Crespo-Facorro
Oct 6, 2009·Pediatrics International : Official Journal of the Japan Pediatric Society·Yoshiaki SaitoKoichi Asai
Jan 21, 2010·Psychological Medicine·J Moncrieff, J Leo
Apr 3, 2010·The American Journal of Psychiatry·David M GardnerRoss J Baldessarini
Feb 22, 2012·Schizophrenia Research·Farzin IraniRuben C Gur
May 8, 2013·Brain : a Journal of Neurology·Rebecca J Von Der HeideIngrid R Olson
Jun 8, 2013·AJNR. American Journal of Neuroradiology·M FilippiE Sacchetti
Nov 8, 2014·Annals of Neurology·Kenichi OishiArgye E Hillis
Nov 27, 2014·Frontiers in Behavioral Neuroscience·Maria JalbrzikowskiCarrie E Bearden
Mar 20, 2015·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Arvind CaprihanJuan R Bustillo
Mar 5, 2016·Social Cognitive and Affective Neuroscience·David B FischerBarbara A Dworetzky
Nov 14, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Lars MarstallerDavid C Reutens
Apr 10, 2018·Trends in Cognitive Sciences·Yin Wang, Ingrid R Olson
May 14, 2018·Neuroscience and Biobehavioral Reviews·Emma J BubbJohn P Aggleton

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