Uncommon complication of anticoagulant therapy: pituitary hemorrhage

La Revue de médecine interne
O DupuyB Bauduceau

Abstract

Pituitary apoplexy is well known as the first manifestation of pituitary tumour. Conversely, haemorrhage of a pituitary adenoma, revealed by anticoagulant therapy, is very uncommon. Two weeks after initiation of anticoagulant therapy for a deep venous thrombosis, an 83-year-old woman presented with intracranial hypertension and blindness. CT-scan revealed pituitary hematoma within a large adenoma. Three months after surgery, partial visual defect persisted in association with panhypopituitarism. When pituitary disorder is known, hemorrhage risk should be taken into account in the prescription of anticoagulant therapy.

References

Dec 20, 2007·Neurosurgery·Patrick L SempleEdward R Laws

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Citations

Jan 7, 2016·Journal of Endocrinological Investigation·L GiammatteiM Locatelli
Mar 22, 2016·La Revue de médecine interne·S El AoudM Abid

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