Uncommon pediatric tumors of the posterior fossa: pathologic and molecular features

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
C Dunham

Abstract

Three tumors are commonly encountered in the posterior fossa of children: pilocytic astrocytoma (PA), medulloblastoma (MB), and ependymoma. However, a variety of additional tumors may occasionally be appreciated. Appropriate and successful treatment of these less common cases is predicated upon correct pathologic diagnosis. Reviewed herein are five less common tumors that may affect the posterior fossa of children: (1) "embryonal tumor with multilayered rosettes" (ETMR); (2) "cribriform neuroepithelial tumor" (CRINET); (3) "rosette-forming glioneuronal tumor" (RGNT); (4) "diffuse pilocytic astrocytoma" (dPA); and, (5) "desmoplastic small round cell tumor" (DSRCT). Each of the foregoing has a varying predilection for children and a posterior fossa location. For example, RGNT by definition arises in association with the 4th ventricle; while the mean age of those afflicted is 33, children may also be affected. Likewise, descriptions of dPA are generally restricted to the posterior fossa, and in particular, the cerebellum of children. Alternatively, DSRCT is a form of undifferentiated sarcoma that characteristically originates in the abdomen of children, but on occasion arises from the tentorium of young adults and children. The re...Continue Reading

References

Sep 1, 1984·Neurosurgery·L PalmaP Celli
Jan 1, 1996·The American Journal of Surgical Pathology·V TisonJ Rosai
Oct 5, 2001·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·C H Rickert, W Paulus
Apr 30, 2002·The American Journal of Surgical Pathology·Takashi KomoriTakanori Hirose
Jul 10, 2007·Acta Neuropathologica·David N LouisPaul Kleihues
Apr 10, 2008·The Journal of Clinical Investigation·Stefan PfisterPeter Lichter
Jun 19, 2008·Pediatric Blood & Cancer·Karim BouchirebJacques Grill
Mar 6, 2009·Virchows Archiv : an International Journal of Pathology·Luciano NederFredric B Meyer
Nov 17, 2009·Journal of Neuropathology and Experimental Neurology·Martin HasselblattWerner Paulus
Jun 10, 2010·Acta Neuropathologica·Werner Paulus, Paul Kleihues
Sep 16, 2011·Acta Neuropathologica·George M IbrahimCynthia Hawkins
Oct 15, 2011·Acta Neuropathologica·Benjamin EllezamMark R Gilbert
Jan 14, 2012·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Ji Young ParkSang Pyo Kim
Apr 14, 2012·Human Pathology·Christopher DunhamPaul Steinbok
Jun 20, 2012·Journal of Neuropathology and Experimental Neurology·Cristiane M IdaCaterina Giannini
Dec 18, 2012·Journal of Neuropathology and Experimental Neurology·Craig Horbinski
Feb 5, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Joanne ZhangCory Adamson
Mar 19, 2013·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Michael A ArnoldChristopher R Pierson
May 9, 2014·Journal of Neuropathology and Experimental Neurology·Marco GessiTorsten Pietsch

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Citations

Feb 17, 2019·Journal of Neurosurgery. Pediatrics·Constanze Buus-GehrigKonrad Bochennek
Oct 16, 2019·Journal of Pediatric Hematology/oncology·Rishab BharadwajJulius X Scott
Dec 28, 2017·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Bruce R Pawel
Mar 29, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Yazeed Al KrinaweElvis J Hermann
Mar 7, 2020·Frontiers in Cell and Developmental Biology·Abbye E McEwenChristina M Lockwood
Jun 22, 2021·Pediatric Blood & Cancer·Arnault Tauziède-EspariatPascale Varlet

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