PMID: 7940102Jul 1, 1994Paper

Uncomplicated stereotactic and open neurosurgical procedures in patients with factor VII deficiency

Surgical Neurology
S E DoranD A Ross

Abstract

Factor VII deficiency is characterized by epistaxis, bruising, hemarthrosis, menorrhagia, gastrointestinal bleeding, hematuria, and intracranial hemorrhage during infancy. Causes of acquired factor VII deficiency include liver disease, Vitamin K deficiency, and warfarin administration. Congenital factor VII deficiency is an autosomal recessive disorder, with the homozygotes having a severe deficiency and the heterozygotes a moderate deficiency of factor VII. Orthopedic, gynecological, cardiothoracic, and abdominal surgical procedures have been successfully performed in patients with factor VII deficiency both with and without factor VII replacement. We present two patients with moderate and moderately severe factor VII deficiency who successfully underwent intracranial procedures using plasma during the perioperative period for factor VII replacement. One patient successfully underwent stereotactic placement of mesial temporal lobe depth electrodes and subdural strip electrodes followed by anterior temporal lobectomy for medically refractory seizures. The second patient successfully underwent craniotomy for an olfactory groove meningioma. No bleeding complications were encountered with any of the three intracranial procedures p...Continue Reading

References

Apr 1, 1988·The American Journal of Medicine·T KuzelJ Baron
Aug 1, 1964·The American Journal of Medicine·V J MARDER, N R SHULMAN

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Citations

Aug 16, 2002·British Journal of Haematology·David J Perry
Jan 5, 1999·Haemophilia : the Official Journal of the World Federation of Hemophilia·J Ingerslev, H L Kristensen
Dec 28, 2007·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·James C BartonSean O'Malley
May 26, 2018·Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko·A Yu Lubnin

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