Uncontrolled Antegrade Pulmonary Blood Flow and Delayed Fontan Completion After the Bidirectional Glenn Procedure: Real-World Outcomes in China

The Annals of Thoracic Surgery
Tao ZhangHao Zhang

Abstract

Given the low rate of Fontan completion, an aggressive policy for maintaining antegrade pulmonary blood flow (AnPBF) during the bidirectional Glenn procedure (BDG) was developed for the functional single ventricle. From 2008 to 2013, 294 patients who underwent the BDG were divided into two groups: group 1 (uncontrolled AnPBF, n = 270) and group 2 (controlled AnPBF, n = 24). Pulmonary artery banding was performed because of the high central venous pressure in group 2. In group 1, the patients who underwent BDG from 2008 to 2012 were further divided into group DF (delayed Fontan completion, n = 109) and group FC (Fontan completion, n = 42). The Fontan completion rate was 16.3%, and the average interval time was 2.2 ± 1.1 years. The delay of Fontan completion did not reduce body weight gain or the survival rate. Furthermore, oxygen saturation was slightly reduced in group DF. Although no impairments of heart function were observed, the uncontrolled AnPBF in group DF resulted in an increase in ventricular end-diastolic diameter and aggravation of atrioventricular valve regurgitation over 24 months after BDG. Logistic regression analysis revealed that systemic right ventricular morphology was a risk factor for the aggravation of val...Continue Reading

References

Sep 2, 1998·The Annals of Thoracic Surgery·D B McElhinneyV M Reddy
Aug 7, 2003·The Annals of Thoracic Surgery·Yoshihisa TanoueKunitaka Joh
Oct 30, 2004·The Annals of Thoracic Surgery·Andrew J LodgeJ William Gaynor
Sep 2, 2005·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Nelson AlphonsoDavid Anderson
Feb 14, 2007·Circulation·Paul KhairyLise-Andrée Mercier
Jun 30, 2007·The Journal of Thoracic and Cardiovascular Surgery·Mark A ScheurerScott M Bradley
Mar 22, 2008·The Annals of Thoracic Surgery·Davide F CalvarusoCarlo F Marcelletti
Jun 7, 2008·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Christian SchreiberRüdiger Lange
Sep 25, 2008·Asian Cardiovascular & Thoracic Annals·Suchaya SilvilairatWeerachai Nawarawong
Jun 4, 2010·Asian Cardiovascular & Thoracic Annals·Madhusudan GanigaraRaghavan Suresh Kumar Nair
Apr 29, 2011·The Annals of Thoracic Surgery·Andrew C FioreKenneth Schowengerdt
Dec 27, 2011·The Annals of Thoracic Surgery·Timothy M LeeEric J Devaney
Mar 1, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sébastien GérelliPascal R Vouhé
Apr 24, 2012·The Annals of Thoracic Surgery·Ymkje J van SlootenTjark Ebels
Jan 17, 2013·The Journal of Thoracic and Cardiovascular Surgery·Sunita J FernsMichel N Ilbawi
Nov 26, 2013·The Journal of Thoracic and Cardiovascular Surgery·Zhan HuShengshou Hu

❮ Previous
Next ❯

Citations

Sep 9, 2017·General Thoracic and Cardiovascular Surgery·Takashi KidoHajime Ichikawa
Oct 4, 2018·Congenital Heart Disease·Martin A Chacon-PortilloCarlos M Mery
Jul 11, 2020·Seminars in Cardiothoracic and Vascular Anesthesia·Ray S ChoiMorgan L Brown
Oct 20, 2017·Interactive Cardiovascular and Thoracic Surgery·Tao YanWeida Zhang
Oct 1, 2020·Journal of Cardiothoracic Surgery·Ryosuke KowatariIkuo Fukuda
Oct 1, 2018·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Sachin TalwarBalram Airan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomegaly

Cardiomegaly, known as an enlarged heart, is a multifactorial disease with different pathophysiological mechanisms. Hypertension, pregnancy, exercise-induced and idiopathic causes are some mechanisms of cardiomegaly. Discover the latest research of cardiomegaly here.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.