Underestimated impact of antibiotic misuse in outpatient children

Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
N CassirJ-C Lagier

Abstract

The judicious prescription of antibiotics has become a central focus of professional and public-health measures to combat the spread of resistant organisms. It also seems important to consider the other impacts and determinants of antibiotic misuse. Evaluating the ambulatory antibiotic prescription for common infections in patients secondarily hospitalized as well as the consequences and determinants of this prescription. Study conducted over a period of 6 months between May and November 2008, during which 52 children aged between 3 months and 15 years, hospitalized in the pediatric hospital of Aix-en-Provence, were recruited. The reason for the pediatric emergency department visit was persistent symptoms or new symptoms over 48 h of ambulatory antibiotic prescription. The ambulatory antibiotic prescription was compared with current practice guidelines, and clinical progression after hospitalization was also analyzed. Afterwards, the determinants of this overprescription in ambulatory practice were investigated through a telephone questionnaire. Seventy-five percent of the antibiotic prescriptions were inappropriate, 60 % of which could potentially have been avoided with had an adequate and recommended practices been followed. ...Continue Reading

References

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Citations

May 7, 2013·PloS One·Emilie PascheChristian Lovis
Aug 21, 2013·The Pediatric Infectious Disease Journal·Ana BrettMike Sharland

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