Underlying and immediate causes of death in patients with idiopathic pulmonary fibrosis

BMC Pulmonary Medicine
Miia KärkkäinenRiitta Kaarteenaho

Abstract

The most common cause of death of patients with idiopathic pulmonary fibrosis (IPF) has been reported to be the lung disease itself and mortality from IPF appears to be increasing. However, the causes of death in patients with IPF taking into account differences between genders and smoking histories as well as disease progression, have not been previously explored. Retrospective data from hospital register and death certificates from national database of IPF patients treated in Kuopio University Hospital (KUH) from 2002 to 2012 were collected. Mortality was also explored from the death registry database via ICD-10 code J84 revealing the numbers of deaths from pulmonary fibrosis in Finland from 1998 to 2015. Out of 117 deaths, 26.5% were females and 73.5% males in KUH. The most common underlying causes of death were IPF 67.5% and ischemic heart diseases 14.8%. More males died for reasons other than IPF (39.5%) compared to females (12.9%) (p = 0.007). Pneumonia as the immediate cause of death was more common in males (27.9%) than in females (3.2%) (p = 0.004) and in ex-smokers (32.7%) compared to non-smokers (9.3%) (p = 0.007). Death register based mortality from pulmonary fibrosis is increasing in Finland. Even though the overal...Continue Reading

References

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Aug 24, 2017·Respiratory Research·Miia KärkkäinenRiitta Kaarteenaho

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Citations

Dec 1, 2019·BMC Pulmonary Medicine·Miia KärkkäinenRiitta Kaarteenaho
Apr 9, 2020·BMJ Open Respiratory Research·Johanna SalonenRiitta Kaarteenaho
Jul 26, 2018·Medical Sciences : Open Access Journal·Paloma Millan-BilliDiego Castillo
Nov 28, 2019·BMC Pulmonary Medicine·Dimitrios KalafatisGiovanni Ferrara
Oct 4, 2019·European Respiratory Review : an Official Journal of the European Respiratory Society·Antonella CaminatiSergio Harari
Nov 25, 2020·Molecular Biology Reports·Yue FangPengxiu Cao
Sep 15, 2020·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Johanna SalonenRiitta Kaarteenaho

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BETA
biopsies

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SPSS Statistics

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