Underlying Medical Conditions Associated With Severe COVID-19 Illness Among Children.

JAMA Network Open
Lyudmyla KompaniyetsAlyson B Goodman

Abstract

Information on underlying conditions and severe COVID-19 illness among children is limited. To examine the risk of severe COVID-19 illness among children associated with underlying medical conditions and medical complexity. This cross-sectional study included patients aged 18 years and younger with International Statistical Classification of Diseases, Tenth Revision, Clinical Modification code U07.1 (COVID-19) or B97.29 (other coronavirus) during an emergency department or inpatient encounter from March 2020 through January 2021. Data were collected from the Premier Healthcare Database Special COVID-19 Release, which included data from more than 800 US hospitals. Multivariable generalized linear models, controlling for patient and hospital characteristics, were used to estimate adjusted risk of severe COVID-19 illness associated with underlying medical conditions and medical complexity. Underlying medical conditions and medical complexity (ie, presence of complex or noncomplex chronic disease). Hospitalization and severe illness when hospitalized (ie, combined outcome of intensive care unit admission, invasive mechanical ventilation, or death). Among 43 465 patients with COVID-19 aged 18 years or younger, the median (interquart...Continue Reading

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Citations

Sep 3, 2021·Pediatric Pulmonology·Cassidy Du BerryDanielle Wurzel
Sep 4, 2021·Journal of Paediatrics and Child Health
Sep 28, 2021·Childhood Obesity·Heidi M BlanckRuth Petersen
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Dec 4, 2021·Clinical Pediatrics·Nina GuoMichael Crocetti

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Software Mentioned

Stata
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Clinical Classifications Software Refined ( CCSR )
R Project for Computing

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