PMID: 9181226Jun 1, 1997Paper

Underlying pathology in mammary Paget's disease

Annals of Surgical Oncology
J H YimG M Doherty

Abstract

Management of patients with mammary Paget's disease is controversial; recent recommendations range from primary radiotherapy to modified radical mastectomy. This review correlates associated breast findings with disease stage and outcome to help guide evaluation and treatment. Retrospective review of clinical, mammographic and pathologic data from 38 women with mammary Paget's disease treated between 1979 and 1995 was performed. Mastectomies were performed on all but two patients with the entire breast and lymph nodes evaluated for histopathologic evidence of carcinoma. Underlying carcinoma (ductal carcinoma in situ and/or invasive ductal cancer) was found in most patients (92%) even when no palpable mass was evident (85%); this carcinoma is often multifocal (73%). Mammography fails to identify the underlying disease in many patients with no palpable mass and multifocal underlying disease (64%). Patients with Paget's disease and a palpable mass have a much greater incidence of invasive cancer, multifocal lesions, and positive lymph nodes, and have worse survival. Although some patients with Paget's disease might be well treated by breast conservation therapy, many patients have underlying multifocal carcinoma (including invasiv...Continue Reading

References

Jun 1, 1991·The British Journal of Surgery·A R DixonR W Blamey
Apr 1, 1990·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·P BulensE van der Schueren
Jun 1, 1988·The American Journal of Dermatopathology·W S Wood, C Hegedus
Apr 1, 1989·Cancer·S Edeiken
Sep 1, 1989·Radiology·D M Ikeda, I Andersson
Oct 1, 1987·International Journal of Radiation Oncology, Biology, Physics·A FourquetJ R Vilcoq
May 1, 1970·American Journal of Surgery·S J Kister, C D Haagensen
Jun 1, 1970·Annals of Surgery·F C NanceW F Becker
Sep 1, 1970·Cancer·R AshikariJ A Urban
Aug 1, 1981·Cancer·J F Paone, R R Baker
Aug 15, 1980·Cancer·P P RosenD E Kinne
Mar 1, 1994·Clinical Radiology·R H Sawyer, D L Asbury

❮ Previous
Next ❯

Citations

Jul 28, 2001·American Journal of Clinical Oncology·W FuS C Young
Oct 10, 2006·Breast Cancer Research and Treatment·Shaheen ZakariaAmy C Degnim
Oct 13, 2009·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Yongxi SongChengzhong Xing
Aug 21, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Shan ZhengYou-Lin Qiao
Aug 17, 2012·The American Journal of Surgical Pathology·Xiuzhen DuanConstance T Albarracin
Apr 23, 2013·Case Reports in Radiology·Eleonora GaspariGiovanni Simonetti
Jul 24, 2015·Annals of Surgical Oncology·Stephanie M WongMehra Golshan
Jul 16, 2015·The British Journal of Surgery·S HelmeA Agrawal
Nov 7, 2000·Journal of Clinical Pathology·J Lloyd, A M Flanagan
Apr 24, 2007·Journal of the European Academy of Dermatology and Venereology : JEADV·J Kanitakis
Feb 2, 2008·Breast Cancer Research and Treatment·Mujgan CaliskanAlberto Luini
Aug 6, 2020·Journal of Medical Case Reports·Lina ChoridahSumadi Lukman Anwar
Sep 14, 2004·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·S OhiraI Konishi
May 19, 2005·The American Journal of Dermatopathology·Joseph H WillmanJames E Fitzpatrick
May 2, 2007·Advances in Anatomic Pathology·Rohit Bhargava, David J Dabbs
May 26, 2005·Annals of Surgical Oncology·Kazumi KawaseKelly K Hunt
Apr 2, 2015·Anais Brasileiros De Dermatologia·Lauro Lourival Lopes FilhoNobuo Matsunaga
Sep 21, 2018·The American Journal of Dermatopathology·Angel Fernandez-FloresJesus Cuevas
Aug 11, 2006·World Journal of Surgical Oncology·Monica GiovanniniAnnamaria Molino
Jun 12, 2012·International Journal of Surgical Oncology·Daniel Xavier Choi, Kimberly J Van Zee
Mar 25, 2016·The Indian Journal of Surgery·Vasu Reddy Challa, Vijayalakshmi Deshmane
Jan 29, 2008·Journal of the American College of Surgeons·Mary MorroghTari A King

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

Related Papers

The British Journal of Radiology
D VerniersC De Wolf-Peeters
The Nebraska Medical Journal
A G ThorsonJ Oliverius
Nihon geka hokan. Archiv für japanische Chirurgie
N TanigawaK Tonozuka
Nederlands tijdschrift voor geneeskunde
M K Polano
Prensa médica argentina
J M ElverdinE I Noval
© 2021 Meta ULC. All rights reserved