Underreporting of Vestibular Schwannoma Incidence Within National Brain Tumor and Cancer Registries in the United States.

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
John P MarinelliMatthew L Carlson

Abstract

Reports using large brain tumor and cancer registries suggest that the incidence of vestibular schwannoma is considerably lower in the United States compared with other countries. The current study compares the incidence and disease characteristics of vestibular schwannoma within a large tertiary referral center's brain tumor and cancer registry using nationally mandated reporting protocols to disease incidence in the same population using an externally validated population-based consortium. Population-based study spanning 1,945,007 person-years. Large tertiary referral center. Adults with sporadic vestibular schwannoma. Disease incidence rates from 2004 to 2016. From 2004 to 2016, the incidence of vestibular schwannoma in the tumor registry was 1.3 per 100,000 person-years whereas the population-based cohort had an incidence of 4.4 per 100,000 person-years. From 2012 to 2016, the incidence in the tumor registry was 1.4 per 100,000 person-years compared with 5.2 in the population-based cohort. Patients within the population-based cohort were significantly more likely to have smaller tumors at diagnosis (78% intracanalicular versus 45%; p = 0.004) and consequently more likely to undergo management consisting of observation with ...Continue Reading

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Mar 10, 2020·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·John P MarinelliMatthew L Carlson

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Citations

Apr 27, 2021·Neuro-oncology·John P Marinelli, Matthew L Carlson
Sep 1, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·John P MarinelliIsaac D Erbele

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