Understanding COPD: A vision on phenotypes, comorbidities and treatment approach

Revista Portuguesa De Pneumologia
E FragosoGI COPD--Interest Group on Chronic Obstructive Pulmonary Disease

Abstract

Chronic Obstructive Pulmonary Disease (COPD) phenotypes have become increasingly recognized as important for grouping patients with similar presentation and/or behavior, within the heterogeneity of the disease. The primary aim of identifying phenotypes is to provide patients with the best health care possible, tailoring the therapeutic approach to each patient. However, the identification of specific phenotypes has been hindered by several factors such as which specific attributes are relevant, which discriminant features should be used for assigning patients to specific phenotypes, and how relevant are they to the therapeutic approach, prognostic and clinical outcome. Moreover, the definition of phenotype is still not consensual. Comorbidities, risk factors, modifiable risk factors and disease severity, although not phenotypes, have impact across all COPD phenotypes. Although there are some identified phenotypes that are fairly consensual, many others have been proposed, but currently lack validation. The on-going debate about which instruments and tests should be used in the identification and definition of phenotypes has contributed to this uncertainty. In this paper, the authors review present knowledge regarding COPD pheno...Continue Reading

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Citations

Mar 2, 2016·Revista Portuguesa De Pneumologia·M Miravitlles
Mar 5, 2016·Revista Portuguesa De Pneumologia·A J FerreiraUNKNOWN GI DPOC-Grupo de Interesse na Doença Pulmonar Obstrutiva Crónica
Jul 1, 2020·Terapevticheskiĭ arkhiv·S N AvdeevE V Kusraeva

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