Understanding emotion and emotional scarring in recurrent depression

Comprehensive Psychiatry
Gerard van RijsbergenClaudi L H Bockting

Abstract

A single-item assessment of sad mood after remission from MDD is predictive of relapse, yet the mechanisms that play a role in depressive relapse remain poorly understood. In 283 patients, remitted from recurrent depression (DSM-IV-TR criteria; HAM-D17 score ≤ 10), we examined emotional scarring, that is, whether the number of previous depressive episodes was associated with higher levels of sad mood as assessed with a 1-item Visual Analogue Mood Scale (VAMS). We then fitted a cross-sectional multivariate regression model to predict sad mood levels, including the Dysfunctional Attitude Scale Version-A, cognitive reactivity (Leiden Index of Depression Sensitivity), Ruminative Response Scale, and Everyday Problem Checklist. Patients with greater numbers of prior episodes experienced higher levels of sad mood after remission. In multivariate regression, intensity of daily stress and dysfunctional beliefs were associated with the VAMS (Adj. R(2)=.091) although not over and above depressive symptomatology (Adj. R(2)=.114). Cognitive reactivity was not associated with sadness. Our finding that patients with more previous MDEs reported higher levels of sad mood while remitted could be indicative of emotional scarring. Dysfunctional be...Continue Reading

References

May 1, 1996·Psychological Medicine·A J RushM H Trivedi
Feb 27, 2003·Journal of Consulting and Clinical Psychology·David J A DozoisJay K Brinker
Jan 14, 2004·Psychological Science·Richard E LucasEd Diener
Jul 5, 2006·Archives of General Psychiatry·Zindel V SegalTom Buis
Jul 18, 2006·The Journal of Clinical Psychiatry·Claudi L H BocktingUNKNOWN Depression Evaluation Longitudinal Therapy Assessment Study Group
Sep 4, 2007·The British Journal of Psychiatry : the Journal of Mental Science·Marieke WichersJim Van Os
Aug 8, 2008·Behaviour Research and Therapy·Nicholas J Moberly, Edward R Watkins
Aug 19, 2008·Behaviour Research and Therapy·Ros Lethbridge, Nicholas B Allen
Feb 18, 2010·The American Journal of Psychiatry·Leslie C MoreyAndrew E Skodol
Sep 22, 2010·Journal of Personality and Social Psychology·Peter KuppensFrancis Tuerlinckx
Oct 25, 2011·Clinical Psychology Review·Shadi BeshaiLeanne Quigley
Jan 19, 2012·Journal of Abnormal Psychology·Christopher J HopwoodRobert F Krueger
Aug 22, 2012·Acta Psychiatrica Scandinavica·N JacobsM Wichers
Mar 13, 2013·Journal of Consulting and Clinical Psychology·Gerard D van RijsbergenAart H Schene
Mar 28, 2013·Psychological Science·Susan T CharlesDavid M Almeida
Jul 30, 2014·Psychiatry Research·Gerard D van RijsbergenClaudi L H Bockting
Nov 1, 2010·Psychology and Psychotherapy·Steven N Carr, Andrew J P Francis

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.