Understanding lupus: fishing genes out of mice and men

Immunity
Tim J Vyse

Abstract

In this issue of Immunity, the Coronin-1A gene Coro1a, which regulates cytoskeletal structure, is shown by Haraldsson et al. (2007) to be a surprising disease-susceptibility gene that contributes to the spontaneous systemic autoimmunity in the MRL mouse, a model of systemic lupus erythematosus.

References

Dec 6, 2002·Nature·Claire M WadeMark J Daly
Jan 18, 2008·Immunity·M Katarina HaraldssonDwight H Kono

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Citations

May 6, 2010·European Journal of Human Genetics : EJHG·David L MorrisTimothy J Vyse
Jun 27, 2012·Current Opinion in Rheumatology·David L Morris, Timothy J Vyse
Jan 1, 2008·Cytogenetic and Genome Research·T PtacekJ C Edberg

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