Understanding nature's residual strain engineering at the human dentine-enamel junction interface

Acta Biomaterialia
Tan SuiA M Korsunsky

Abstract

Human dental tissue is a hydrated biological mineral composite. In terms of volume and mass, a human tooth mainly consists of dentine and enamel. Human dental tissues have a hierarchical structure and versatile mechanical properties. The dentine enamel junction (DEJ) is an important biological interface that provides a durable bond between enamel and dentine that is a life-long success story: while intact and free from disease, this interface does not fail despite the harsh thermo-mechanical loading in the oral cavity. The underlying reasons for such remarkable strength and durability are still not fully clear from the structural and mechanical perspectives. One possibility is that, in an example of residual stress engineering, evolution has led to the formation of a layer of inelastic strain adjacent to the DEJ during odontogenesis (tooth formation). However, due to significant experimental and interpretational challenges, no meaningful quantification of residual stress in the vicinity of the DEJ at the appropriate spatial resolution has been reported to date. In this study, we applied a recently developed flexible and versatile method for measuring the residual elastic strain at (sub)micron-scale utilising focused ion beam (F...Continue Reading

References

May 7, 2003·Proceedings of the National Academy of Sciences of the United States of America·Huajian GaoPeter Fratzl
Oct 4, 2005·The Journal of Prosthetic Dentistry·S N WhiteM L Snead
Jan 29, 2009·Dental Materials : Official Publication of the Academy of Dental Materials·Elsa VennatMichel Degrange
May 7, 2009·Photomedicine and Laser Surgery·Giselle Rodrigues de Sant'annaAldo Brugnera
Apr 20, 2010·Biomaterials·Anke MärtenPaul Zaslansky
May 14, 2011·Journal of the Mechanical Behavior of Biomedical Materials·Y L ChanN M King
Nov 22, 2011·Journal of the Mechanical Behavior of Biomedical Materials·Ines Jimenez-PalomarAsa H Barber
Sep 12, 2012·Autophagy·Daniel J KlionskyBrian Zuckerbraun
Jul 6, 2013·Materials Science & Engineering. C, Materials for Biological Applications·Anjali SinghalDavid C Dunand
Jan 22, 2014·Journal of the Mechanical Behavior of Biomedical Materials·Tan SuiAlexander M Korsunsky
Apr 11, 2015·Journal of Dental Research·T SuiG Landini
Apr 26, 2015·Journal of Biomechanics·Shu-Fen ChuangHsien-Chang Chang

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Citations

Apr 20, 2019·European Journal of Oral Sciences·Tarek A OmranPekka K Vallittu
Dec 30, 2017·Experimental and Therapeutic Medicine·Nina XieZongxiang Liu
Jan 29, 2020·Acta Biomaterialia·Tijana LainovićThomas Dehoux
Jan 2, 2021·International Journal of Molecular Sciences·Andrzej KuczumowMaciej Jarzębski
Mar 16, 2021·Dental Materials : Official Publication of the Academy of Dental Materials·Sungsik YoonHae-Hyoung Lee
Oct 12, 2018·Dental Materials : Official Publication of the Academy of Dental Materials·Nancie CougotJérome Chevalier

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