Understanding of chemoprophylaxis and concordance in inflammatory bowel disease.

World Journal of Gastroenterology : WJG
Adam LowJason Goh

Abstract

To assess patients' understanding for the reasons for taking 5-aminosalicylic acid or ursodeoxycholic acid as chemoprophylaxis against colorectal carcinoma associated with inflammatory bowel disease (IBD). A questionnaire-based study using a 5-point opinion scale was performed. One hundred and ninety-two patients with colitis only and 74 patients with primary sclerosing cholangitis and IBD were invited to take part. Overall response rate was 58%. Sixty-four percent of patients claimed full concordance with chemoprophylaxis for maintenance of remission. Eighty-four percent of patients considered daily concordance during remission to be very important. Seventy-five percent stated they understood the reasons for taking the drugs. However, only 50% of the patients were aware of any link of their condition to bowel cancer. Seventy-nine percent of patients felt their concordance and understanding would be improved if they were informed of the chemoprophylactic potential of the medication. Despite good self-reported concordance, half of the patients were unaware of an association between colitis and bowel cancer. Explaining the potential chemoprophylactic benefits may enhance patients' overall concordance to 5-aminosalicylic acid and ...Continue Reading

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Citations

Oct 22, 2019·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Affifa Farrukh, John F Mayberry
Apr 8, 2016·World Journal of Gastroenterology : WJG·Nick E BurrVenkataraman Subramanian

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