Understanding omega-3's

American Heart Journal
Andrew Paul Defilippis, Laurence S Sperling

Abstract

Omega-3 fatty acids are a subset of polyunsaturated fatty acids found in marine sources as eicosapentaenoic acid and docosahexaenoic acid and in some leafy vegetables, nuts, and oils as alpha-linolenic acid (ALA). The metabolism of omega-3's may explain the cardioprotective effects observed in epidemiologic and experimental studies. Although most data for cardioprotective effects come from studies of marine sources, vegetable sources of omega-3 fatty acids (alpha-linolenic acid) may have similar effects through in vivo conversion to eicosapentaenoic acid and docosahexaenoic acid. This document will provide an overview of omega-3 fatty acids with a focus on specific sources, metabolism, safety issues, and their potential indication for cardiovascular prevention.

References

Jan 21, 1978·Lancet·J Dyerberg, H O Bang
Jan 1, 1990·The American Journal of Clinical Nutrition·T van Vliet, M B Katan
Jan 31, 1985·The New England Journal of Medicine·S B Eaton, M Konner
Sep 25, 1986·The New England Journal of Medicine·A P Simopoulos, N Salem
May 9, 1985·The New England Journal of Medicine·D KromhoutC de Lezenne Coulander
Apr 13, 1995·The New England Journal of Medicine·A AscherioW C Willett
Apr 10, 1997·The New England Journal of Medicine·M L DaviglusR B Shekelle
Apr 1, 1997·European Journal of Clinical Nutrition·S B EatonM J Konner
Jan 10, 1998·JAMA : the Journal of the American Medical Association·C M AlbertJ E Manson
Jan 14, 1999·The New England Journal of Medicine·R Ross
Jun 22, 1999·The New England Journal of Medicine·G D Sloop
Sep 2, 1999·Prostaglandins, Leukotrienes, and Essential Fatty Acids·A P Simopoulos
Sep 9, 1999·The American Journal of Clinical Nutrition·A P Simopoulos
Jul 13, 2000·Archives of General Psychiatry·B K Puri, A D Richardson
Nov 14, 2001·Archives of Internal Medicine·C R Harper, T A Jacobson
Apr 10, 2002·JAMA : the Journal of the American Medical Association·Frank B HuJoAnn E Manson
Apr 12, 2002·The New England Journal of Medicine·Christine M AlbertJing Ma
Jun 13, 2002·European Journal of Clinical Investigation·D C ChanT G Redgrave
Nov 20, 2002·Circulation·Penny M Kris-EthertonUNKNOWN American Heart Association. Nutrition Committee
May 9, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P D TerryT E Rohan
Oct 31, 2003·The New England Journal of Medicine·Thomas W ClarksonGary J Myers
Nov 25, 2003·Archives of Pathology & Laboratory Medicine·Stacy E ForanKent B Lewandrowski
Mar 18, 2004·Primary Care·Michael L Green
Apr 13, 2004·Current Opinion in Clinical Nutrition and Metabolic Care·Graham Burdge
Aug 21, 2004·Preventive Cardiology·Charles R Harper, Terry A Jacobson
Oct 22, 2004·Journal of the American Academy of Nurse Practitioners·Amanda LewisMary E Tiedeman

❮ Previous
Next ❯

Citations

Aug 1, 2009·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Mohd Hanif ZulfakarCharles M Heard
May 28, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Marjan AjamiHamidreza Pazoki-Toroudi
Sep 16, 2010·Current Treatment Options in Cardiovascular Medicine·Andrew Paul DefilippisTerry A Jacobson
Sep 3, 2013·The Proceedings of the Nutrition Society·Matthew Spite
Mar 1, 2012·Food Additives & Contaminants. Part B, Surveillance·Augoustina GalitsopoulouMichael Kontominas
Aug 12, 2009·Lipids in Health and Disease·Breanne M Anderson, David W L Ma
Nov 19, 2013·Cardiovascular Journal of Africa·Maretha Opperman, Spinnler Benade
Aug 24, 2007·The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists·Diane NykampAmy P Wenker
May 27, 2010·Nutrition Reviews·Rebecca WallCatherine Stanton
Jun 5, 2008·Nutrition Reviews·Aliza H StarkRam Reifen
May 27, 2009·International Journal of Food Sciences and Nutrition·Andrew P DeFilippisTerry A Jacobson
Jun 23, 2009·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·W S AnN D Vaziri
Sep 10, 2015·The Journal of Nutritional Biochemistry·Ram ReifenAbraham Nyska
Aug 2, 2008·Clinics in Geriatric Medicine·Angela D Mazza
Sep 28, 2015·Journal of Dairy Science·B Dal BelloG Zeppa
Jul 25, 2015·Journal of Animal Science and Biotechnology·Brian J KerrGerald C Shurson
Jul 4, 2015·Journal of Food Science and Technology·Pei-En Lee, Wee-Sim Choo
Dec 25, 2010·Journal of Dairy Science·G ButlerC Leifert
Oct 18, 2016·Critical Reviews in Food Science and Nutrition·Gelinda DeaconJoseph Tucci
May 27, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Kyu-Bong KimByung-Mu Lee
Nov 23, 2013·Critical Reviews in Food Science and Nutrition·Katie LaneCharles Brennan
Jul 20, 2016·Oxidative Medicine and Cellular Longevity·Jiyuan BuGang Chen
Jul 5, 2007·The Annals of Pharmacotherapy·Jennifer M Malinowski, Kimberly Metka
Mar 7, 2019·Frontiers in Neurology·Lucinda J BlackUNKNOWN Ausimmune Investigator Group
Nov 1, 2018·Current Medicinal Chemistry·Joana CamposEliana B Souto
Aug 10, 2019·European Journal of Clinical Nutrition·Lucinda J BlackUNKNOWN Ausimmune Investigator Group
Dec 9, 2014·American Journal of Physiology. Heart and Circulatory Physiology·Elizabeth F LopezGanesh V Halade
Jul 19, 2017·International Journal of Molecular Sciences·Matteo ManuelliHellas Cena
Jun 21, 2020·Brain Sciences·Mayra Montecillo-AguadoSara Huerta-Yepez
Jul 29, 2017·European Heart Journal Supplements : Journal of the European Society of Cardiology·Michele Massimo GuliziaAttilio Maseri
Apr 25, 2007·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Angela D Mazza, John E Morley
Dec 29, 2018·Nutrients·Maria Alessandra GammoneNicolantonio D'Orazio

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.