Abstract
Statins are first-line for cholesterol lowering and prevention of atherosclerotic cardiovascular disease (ASCVD), but their use is complicated by side effects and potential for drug-drug interactions. Provider-patient communication is the basis of the recommended shared decision-making, but relatively little is known about this in the context of statin use. We surveyed 5014 US adults prescribed a statin for hypercholesterolemia to learn their perspectives on communication with their provider. Ninety-four percent reported currently taking a statin while 6% had stopped. Past users vs current users were more likely to be female, age < 65 years, and to have fewer cardiovascular disease-related comorbidities (hypertension, type 2 diabetes mellitus, and coronary heart disease, respectively). Although 93% of current statin users were taking ≥1 other prescription medications (median of 4), 76% were "not at all"/"not very concerned" about potential drug-drug interactions with their statin, and fewer than one-quarter recalled mention of these from their provider. Ninety-five percent of subjects said it was "extremely"/"somewhat" important that their healthcare provider take "an individualized approach to selecting the right statin," but ...Continue Reading
References
Jun 5, 2003·Acta Tropica·Peter M Schantz, Victor C W Tsang
Aug 5, 2005·The New England Journal of Medicine·Lars Osterberg, Terrence Blaschke
Oct 7, 2005·Pharmacotherapy·David F BlackburnThomas W Wilson
Aug 13, 2010·The Annals of Pharmacotherapy·Devin M MannIan Kronish
Sep 15, 2010·American Journal of Therapeutics·Dale A RubleeLuke Boulanger
Jun 5, 2012·Journal of Clinical Lipidology·Jerome D CohenTerry A Jacobson
Oct 2, 2013·Journal of Clinical Lipidology·Melissa Y WeiTerry A Jacobson
Nov 14, 2013·Journal of the American Pharmacists Association : JAPhA
Jan 2, 2014·Indian Journal of Endocrinology and Metabolism·Soma B RajuK Madhu
Feb 18, 2014·Journal of Clinical Lipidology·Matthew K ItoTerry A Jacobson
May 6, 2014·Journal of Clinical Lipidology·Terry A Jacobson
May 25, 2016·Journal of Multidisciplinary Healthcare·Alaa Althubaiti
Sep 1, 2016·Journal of Clinical Lipidology·Dean G KaralisJerome D Cohen
Sep 1, 2016·Journal of Clinical Lipidology·Eliot A BrintonJerome D Cohen
Apr 25, 2017·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Paul S JellingerMichael Davidson
Dec 15, 2017·Journal of Clinical Lipidology·Terry A JacobsonJerome D Cohen
Citations
Oct 2, 2019·International Journal of Clinical Practice·Michael G KirbyDerek J Rosario
May 17, 2019·Terapevticheskiĭ arkhiv·I V SergienkoS A Boytsov
Jul 12, 2020·British Journal of Clinical Pharmacology·Victor J B HuiskesBartholomeus J F van den Bemt
Aug 21, 2019·Scientific Reports·Huber DanielMooe Thomas
Jan 18, 2019·Circulation Research·Natalie C WardRobert H Eckel
Nov 11, 2020·Journal of the American Heart Association·Sarah T AhmedSalim S Virani
Dec 2, 2020·Journal of Internal Medicine·M CasulaUNKNOWN PROSISA Study Group
Jul 14, 2021·BMJ Open·Tessa MarshallPhyllis Lau
Jan 9, 2022·Journal of General Internal Medicine·Jingzhi YuAbel N Kho