Understanding patient preferences for the treatment of lupus nephritis with adaptive conjoint analysis

Medical Care
Liana FraenkelDick Wittink

Abstract

Incorporation of patient preferences into treatment decisions is an essential component of medical care. Conjoint analysis is an established method of eliciting consumer preferences in market research and is being increasingly used to study patient preferences for health care. To examine the value of Adaptive Conjoint Analysis (ACA), a unique method of performing conjoint analysis, and to evaluate patient treatment preferences. Interactive computer survey. Consecutive women (n = 103) with lupus followed in three community rheumatology practices. ACA was used to assess patients' relative preferences for specific cytotoxic medication characteristics, and to estimate the percentage of women preferring cyclophosphamide over azathioprine for different risk-benefit scenarios. All participants were able to complete the conjoint task in 14 +/-5 minutes. Of the nine medication characteristics studied, efficacy and risk for infection had the greatest impact on preference (each accounting for 20% of the variation in preferences), suggesting that patients consider differences in the risk for infection equally as important as differences in the probability of renal survival. Premenopausal women wanting more children were less likely to choo...Continue Reading

References

Sep 1, 1992·Journal of Clinical Epidemiology·L F Degner, J A Sloan
May 1, 1991·Journal of General Internal Medicine·D J Mazur, D H Hickam
Sep 1, 1990·Journal of Epidemiology and Community Health·B J O'BrienA Calin
Jan 1, 1990·Arthritis and Rheumatism·J F FriesH B Hubert
Oct 1, 1986·Medical Decision Making : an International Journal of the Society for Medical Decision Making·D J Mazur
Jan 1, 1987·Annals of Internal Medicine·J E BalowJ H Klippel
Apr 1, 1985·Annals of Internal Medicine·S GreenfieldJ E Ware
Jan 1, 1983·Social Science & Medicine·C L Kaufmann
Feb 1, 1983·European Journal of Cancer & Clinical Oncology·A CoatesM H Tattersall
Jan 1, 1984·Journal of Chronic Diseases·H A Llewellyn-ThomasJ E Till
May 1, 1995·Patient Education and Counseling·H A Llewellyn-ThomasD E Woermke
Apr 1, 1995·Medical Decision Making : an International Journal of the Society for Medical Decision Making·H A Llewellyn-Thomas
Jul 1, 1994·Medical Decision Making : an International Journal of the Society for Medical Decision Making·D J Mazur, D H Hickam
Jun 1, 1993·Baillière's Clinical Rheumatology·L H Daltroy
Jan 1, 1997·Lupus·F MartinF A Houssiau
Jun 10, 1998·British Journal of Rheumatology·M HoT Pullar
Jul 29, 1998·Medical Decision Making : an International Journal of the Society for Medical Decision Making·M D BrundageP Groome
Jul 29, 1998·Social Science & Medicine·E Guadagnoli, P Ward
Mar 23, 1999·JAMA : the Journal of the American Medical Association·S T BogardusJ F Jekel
Sep 17, 1999·BMJ : British Medical Journal·A Coulter
Jan 19, 2000·Medical Decision Making : an International Journal of the Society for Medical Decision Making·D Feldman-StewartW J Mackillop
Jun 2, 2000·BMJ : British Medical Journal·M Ryan, S Farrar
Apr 28, 2001·Arthritis and Rheumatism·L FraenkelD Felson
Feb 22, 2002·Arthritis and Rheumatism·William P. Arend

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Citations

Nov 15, 2011·Journal of General Internal Medicine·Liana FraenkelHoward Leventhal
Nov 4, 2004·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Parthiv J MahadeviaLiza O'Dowd
Jan 24, 2009·Medical Care·Florina ConstantinescuLiana Fraenkel
Jul 29, 2009·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Liana FraenkelGuadalupe Garcia-Tsao
Nov 9, 2010·Health and Quality of Life Outcomes·Miguel A RuizUNKNOWN GEIDAC Group
May 3, 2013·Applied Health Economics and Health Policy·A Brett HauberF Reed Johnson
Apr 10, 2008·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·A M StiggelboutT P M Vliet Vlieland
Jul 10, 2014·PharmacoEconomics·Michael D ClarkEsther W de Bekker-Grob
Aug 27, 2014·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Inger M JanssenFülöp Scheibler
Oct 6, 2015·Contemporary Clinical Trials·Ravishankar JayadevappaJ Sanford Schwartz
Apr 1, 2009·Arthritis and Rheumatism·Florina ConstantinescuLiana Fraenkel
Aug 7, 2007·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Thomas W Weiss, Colleen A McHorney
Jun 17, 2010·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Arwen H PieterseCorrie A M Marijnen
Sep 13, 2006·Patient Education and Counseling·Liana FraenkelDick Wittink
Aug 11, 2005·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Kathleen M BeusterienJamie C Jordan
Dec 13, 2005·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Mark J AtkinsonSteven L Hass
Sep 29, 2004·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Michael AristidesNikos Maniadakis
May 23, 2008·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Miguel A RuizJosé L Aranguren
May 27, 2003·Lupus·L FraenkelD R Wittink
Mar 1, 2011·Health Informatics Journal·Deborah Beranek Lafky, Thomas A Horan
Mar 8, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David CasarettDavid A Asch
Dec 31, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David J CasarettDavid A Asch
Apr 13, 2004·Arthritis and Rheumatism·Liana FraenkelTerri Fried
May 2, 2012·Medical Decision Making : an International Journal of the Society for Medical Decision Making·I B de GrootUNKNOWN CHOICE-2 Study Group
Dec 17, 2017·Annals of the Rheumatic Diseases·Liana FraenkelCarole Wiedmeyer
Feb 14, 2018·Arthritis Care & Research·Betty HsiaoLiana Fraenkel
Jul 17, 2015·The Journal of Rheumatology·Jasvinder A SinghRichard M Shewchuk
Oct 3, 2006·Arthritis and Rheumatism·Liana FraenkelDick Wittink
Mar 13, 2019·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ravishankar JayadevappaAlan J Wein
Mar 31, 2012·Expert Review of Pharmacoeconomics & Outcomes Research·Richard L StreetRonald M Epstein
Jul 2, 2019·MDM Policy & Practice·Ravishankar JayadevappaMarsha N Wittink
Jun 21, 2020·BMC Medical Informatics and Decision Making·Chiara WhichelloEsther W de Bekker-Grob
Jan 13, 2021·Psychiatric Services : a Journal of the American Psychiatric Association·Nichole GoodsmithAlexander S Young

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