Understanding patient values and the manifestations in clinical research with traditional chinese medicine-with practical suggestions for trial design and implementation

Evidence-based Complementary and Alternative Medicine : ECAM
Wei Mu, Hongcai Shang

Abstract

Objective. To define patient values, identify their manifestations in a randomized clinical trial, and investigate the possible implications for clinical research of traditional Chinese medicine. Methods. We categorized patient values manifestations into patient choice, preference, compliance, and patient-reported outcomes and summarized the underlying personal values through purposeful electronic searches for relevant reports. By hypothesizing a set of positive versus negative circumstances occurring in the enrollment, intervention allocation, treatment, and the follow-up stage of a trial, it is possible to discuss the potential implications of patient values manifestation on a trial with traditional Chinese medicine. Results. Patient values and its manifestations are ubiquitous in the process of clinical research with traditional Chinese medicine. These values may provide motivation for participation or engender the internal and external validity of the study. Conclusions. Trialists should attach sufficient importance to the needs and concerns of individual participant. To incorporate patient values into the design and conduct of a clinical study with traditional Chinese medicine, researchers are recommended to adopt particip...Continue Reading

References

Jul 29, 1989·BMJ : British Medical Journal·C R Brewin, C Bradley
Dec 31, 1993·Annals of the New York Academy of Sciences·J E WennbergA Mulley
Mar 6, 1998·BMJ : British Medical Journal·D J Torgerson, B Sibbald
Mar 13, 1998·Journal of the Royal Society of Medicine·K McPhersonJ E Wennberg
Dec 2, 1999·Journal of Clinical Epidemiology·S RossR Prescott
Mar 5, 2003·Social Science & Medicine·Mary R JanevicNoreen M Clark
Mar 26, 2003·Journal of Clinical Epidemiology·Scott D Halpern
Mar 3, 2005·JAMA : the Journal of the American Medical Association·Michael KingRosalind Lai
Jun 24, 2010·Journal of Empirical Research on Human Research Ethics : JERHRE·Anna H L Floyd, Anne Moyer
May 14, 2011·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Zheng-kun HouLi-juan Li
May 1, 2003·Evaluation and Program Planning·Patrick W Corrigan, Mark S Salzer

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