Understanding the lethal variant of prostate cancer: power of examining extremes.

Cancer Discovery
Ana AparicioSankar N Maity

Abstract

Small cell prostate carcinoma is a lethal variant of castration-resistant prostate cancer. Beltran and colleagues identified overexpression and amplification of both aurora kinase A (AURKA) and the MYCN proto-oncogene in the small cell prostate carcinomas and propose Aurora kinase A as a potential therapeutic target in this disease subset.

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Citations

Jan 12, 2013·European Urology·Behfar Ehdaie, Karim A Touijer
Feb 24, 2015·Oncogene·E Pazarentzos, T G Bivona
May 3, 2015·Endocrine-related Cancer·Jennifer L BishopAmina Zoubeidi
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Mar 24, 2018·BJU International·Ruiqi ChenMartin Gleave
Aug 30, 2018·The Prostate·Yinan LiXuesen Dong
Aug 14, 2019·Archives of Pathology & Laboratory Medicine·Varsha Manucha, John Henegan
Feb 12, 2020·International Journal of Molecular Sciences·Paola OstanoGiovanna Chiorino
Jul 22, 2020·The Prostate·Jagpreet S NandaMagdalena M Grabowska
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Feb 19, 2019·Asian Journal of Urology·Lingfan XuJiaoti Huang
Jul 31, 2020·Physiological Reviews·Arianna GiacominiMarco Presta
Jul 10, 2018·Biochimica Et Biophysica Acta. Reviews on Cancer·Rama SoundararajanSendurai A Mani
Apr 20, 2021·Frontiers in Cell and Developmental Biology·Yongyong YangQi Cao

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