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Understanding type 1 diabetes through genetics: advances and prospects

Nature Reviews. Genetics

Nov 1, 2011

Constantin Polychronakos, Quan Li

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Abstract

Starting with early crucial discoveries of the role of the major histocompatibility complex, genetic studies have long had a role in understanding the biology of type 1 diabetes (T1D), which is one of the most heritable common diseases. Recent genome-wide association studies (GWASs) hav...read more

Mentioned in this Paper

Immune System
Quantitative Trait Loci
Diabetes, Autoimmune
Adaptive Immunity
Resistance, Natural
Genome-Wide Association Study
Genetic Predisposition to Disease
Major Histocompatibility Complex
Entire Immune System
Prophylactic Behavior
7
260
Paper Details
References
  • References88
  • Citations76
12345...
  • References88
  • Citations76
12345...

Understanding type 1 diabetes through genetics: advances and prospects

Nature Reviews. Genetics

Nov 1, 2011

Constantin Polychronakos, Quan Li

PMID: 22005987

DOI: 10.1038/nrg3069

Abstract

Starting with early crucial discoveries of the role of the major histocompatibility complex, genetic studies have long had a role in understanding the biology of type 1 diabetes (T1D), which is one of the most heritable common diseases. Recent genome-wide association studies (GWASs) hav...read more

Mentioned in this Paper

Immune System
Quantitative Trait Loci
Diabetes, Autoimmune
Adaptive Immunity
Resistance, Natural
7
260
Paper Details
References
  • References88
  • Citations76
12345...
  • References88
  • Citations76
12345...

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