Abstract
The purpose of this study was to assess the clinical value and potential impact of contrast-enhanced ultrasound (CEUS) in the characterization of undetermined focal liver lesions (FLLs) in patients with fatty liver. Fifty-two patients (34 men, 18 women) with fatty liver with 67 FLLs (size range, 1-8.6 cm; mean, 4.1 +/- 3.1 cm) undetermined at baseline ultrasound (US) underwent contrast-enhanced US. CEUS examinations were analyzed by two experienced sonologists blinded to the final diagnosis. Readers evaluated by consensus the baseline echogenicity, the dynamic enhancement pattern in comparison with peripheral liver parenchyma. The final diagnosis was based on consensus interpreting of all examinations by another two expert observers with access to histological data. The characterization accuracy, sensitivity, and specificity of CEUS in characterizing the lesion as benign or malignant, and as the correct pathologic type, were analyzed. After CEUS, two hemangiomas, three inflammatory pseudotumors, and one hepatocellular carcinoma were misdiagnosed. The overall characterization accuracy, sensitivity and specificity of CEUS were 91% (61/67), 91.7% (11/12), and 90.9% (50/55), respectively. Forty-three benign lesions were diagnosed a...Continue Reading
References
Jan 1, 1984·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·J C ScatarigeR C Sanders
May 1, 1995·AJR. American Journal of Roentgenology·C ReinholdK J Taylor
Jan 15, 1994·Cancer·M ShimadaK Sugimachi
Aug 1, 1996·AJR. American Journal of Roentgenology·K J NamJ H Lim
Oct 1, 1996·Radiology·J H Oliver, R L Baron
Aug 31, 2000·Radiology·M G JeongK W Kim
Oct 31, 2000·The Journal of Pathology·L P Dehner
Apr 12, 2001·Seminars in Liver Disease·E S Siegelman, M A Rosen
May 29, 2001·Radiology·K W KimB I Choi
Aug 15, 2001·Abdominal Imaging·K KonnoS Watanabe
Aug 21, 2001·European Radiology·C J Harvey, T Albrecht
Aug 30, 2001·Radiology·M J BlomleyR Basilico
Dec 26, 2001·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·K H YoonC G Kim
Oct 22, 2002·AJR. American Journal of Roentgenology·Alexandra von HerbayDieter Häussinger
Nov 7, 2002·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Alexandra von HerbayDieter Häussinger
Oct 11, 2003·European Radiology·Tommaso Vincenzo BartolottaRoberto Lagalla
Aug 10, 2004·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·M Claudon, K A Jäger
Aug 10, 2004·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·T AlbrechtUNKNOWN EFSUMB Study Group
Aug 20, 2004·Alcoholism, Clinical and Experimental Research·Soo Ryang KimMasatoshi Kudo
Sep 10, 2004·Abdominal Imaging·C Nicolau, C Brú
Feb 9, 2005·European Radiology·A Bleuzen, F Tranquart
Feb 23, 2005·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Hong DingChao-Lun Li
Mar 25, 2005·AJR. American Journal of Roentgenology·Se Hyung KimByung Ihn Choi
Apr 23, 2005·Japanese Journal of Clinical Oncology·Rieko NishimuraAkira Kurita
Aug 27, 2005·Ultraschall in der Medizin : Organ der Deutschen Gesellschaft für Ultraschall in der Medizin, [der] Österreichischen Gesellschaft für Ultraschall in der Medizin, [der] Schweizerischen Gesellschaft für Ultraschall in Medizin und Biologie·D StrobelT Bernatik
Dec 17, 2005·AJR. American Journal of Roentgenology·Carlos NicolauConcepcio Brú
Oct 31, 2006·World Journal of Gastroenterology : WJG·Kazushi NumataKatsuaki Tanaka
Dec 21, 2006·European Radiology·Tommaso Vincenzo BartolottaRoberto Lagalla
Mar 17, 2007·Journal of Clinical Ultrasound : JCU·Yang WangYongyan Gao
Apr 28, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Christoph F DietrichAndre Ignee
Nov 21, 2007·World Journal of Gastroenterology : WJG·Stanislas-H MorinSimon D Taylor-Robinson
Citations
Jan 6, 2009·Journal of Gastroenterology and Hepatology·Yang-Yi Ong, Robert N Gibson
Jul 13, 2011·Radiology·Anass AnayeJean-Yves Meuwly
Aug 19, 2011·Journal of Cancer Research and Clinical Oncology·Yang GuangYing Huang
Jun 1, 2011·Journal of Ultrasound·O CatalanoA Gallipoli D'Errico
May 3, 2011·Ultrasound in Medicine & Biology·Limei XieYing Huang
May 15, 2015·Bioscience Trends·Liang FangYue Chen
Jun 12, 2013·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Ahmed AlzaraaDavid Lloyd
Feb 26, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Mireen Friedrich-RustJoerg Bojunga
May 9, 2015·Insights Into Imaging·Arianna LorussoMaria Assunta Cova
Feb 5, 2015·European Journal of Radiology·C TrenkerC Görg
Sep 19, 2014·European Radiology·Maxime RonotValérie Vilgrain
Sep 10, 2016·The British Journal of Radiology·Vasileios RafailidisMaria E Sellars
Feb 4, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Elsa Rosado, Michael Riccabona
Dec 1, 2017·European Radiology·Menglin WuXuening Zhang
Dec 9, 2017·Expert Review of Gastroenterology & Hepatology·Maha Hasab AllahHeba Omar
Feb 5, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Rivka KessnerNami Azar
Aug 28, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Li-Ping LiuLi-Chun An
May 13, 2021·Pediatric Radiology·Cheng FangM Beth McCarville