Undifferentiated carcinoma of the parotid gland. Case report with electron microscopic findings

Virchows Archiv. A, Pathological Anatomy and Histopathology
Y YakuK Nagao

Abstract

Two cases of undifferentiated carcinoma of the parotid gland were studied by light and electron microscopy. Light microscopy showed nests of ovoid cells with scanty cytoplasm and pyknotic nuclei in two cases. One case was the small-cell type, and another one was the large-cell type histopathologically. Electron microscopy showed two distinct cell types in each tumor: Case 1 (small-cell type). - An epithelial-like cell, and an irregular-shaped cell containing bundles of filaments suggesting myoepithelial differentiation. Case 2 (large-cell type). - An epithelial-like cell, and a large cell containing secretory-like granules. These findings support a salivary duct epithelial origin for these tumors.

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Citations

Jan 1, 1984·Virchows Archiv. A, Pathological Anatomy and Histopathology·K DonathJ Lentrodt
Feb 21, 2004·American Journal of Otolaryngology·Allison T Pontius, Yadranko Ducic
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Mar 15, 2016·The Laryngoscope·Kevin Y ZhanEric J Lentsch
Jan 7, 2005·American Journal of Otolaryngology·Yen-Chun LinJeh-En Tzeng
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Jan 1, 1991·The Annals of Otology, Rhinology, and Laryngology·J G Batsakis, M A Luna

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