Undisclosed financial ties between guideline writers and pharmaceutical companies: a cross-sectional study across 10 disease categories

BMJ Open
Ray MoynihanLisa Bero

Abstract

To investigate the proportion of potentially relevant undisclosed financial ties between clinical practice guideline writers and pharmaceutical companies. Cross-sectional study of a stratified random sample of Australian guidelines and writers. Guidelines available from Australia's National Health and Medical Research Council guideline database, 2012-2014, stratified across 10 health priority areas. 402 authors of 33 guidelines, including up to four from each area, dependent on availability: arthritis/musculoskeletal (3); asthma (4); cancer (4); cardiovascular (4); diabetes (4); injury (3); kidney/urogenital (4); mental health (4); neurological (1); obesity (1). For guideline writers with no disclosures, or who disclosed no ties, a search of disclosures in the medical literature in the 5 years prior to guideline publication identified potentially relevant ties, undisclosed in guidelines. Guidelines were included if they contained recommendations of medicines, and writers included if developing or writing guidelines. Proportions of guideline writers with potentially relevant undisclosed financial ties to pharmaceutical companies active in the therapeutic area; proportion of guidelines including at least one writer with a potenti...Continue Reading

References

Dec 5, 2006·Health Research Policy and Systems·Elizabeth A Boyd, Lisa A Bero
May 19, 2010·Annals of Internal Medicine·Gordon GuyattHolger Schünemann
May 7, 2013·BMC Medical Ethics·Julie Bolette Brix BindslevAndreas Lundh
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Dec 23, 2017·JAMA Otolaryngology-- Head & Neck Surgery·Jarryd HornMatt Vassar

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Citations

May 29, 2019·The American Journal of Bioethics : AJOB·Jane JohnsonWendy A Rogers
May 18, 2021·Mayo Clinic Proceedings. Innovations, Quality & Outcomes·Sahar TabatabavakiliSamir C Grover
Nov 5, 2019·Paediatric Respiratory Reviews·David IsaacsAnne Preisz

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