Undulation contributions to the area compressibility in lipid bilayer simulations.

Biophysical Journal
Qaiser Waheed, O Edholm

Abstract

It is here shown that there is a considerable system size-dependence in the area compressibility calculated from area fluctuations in lipid bilayers. This is caused by the contributions to the area fluctuations from undulations. This is also the case in experiments. At present, such a contribution, in most cases, is subtracted from the experimental values to obtain a true area compressibility. This should also be done with the simulation values. Here, this is done by extrapolating area compressibility versus system size, down to very small (zero) system size, where undulations no longer exist. The area compressibility moduli obtained from such simulations do not agree with experimental true area compressibility moduli as well as the uncorrected ones from contemporary or earlier simulations, but tend, instead, to be approximately 50% too large. As a byproduct, the bending modulus can be calculated from the slope of the compressibility modulus versus system-size. The values obtained in this way for the bending modulus are then in good agreement with experiment.

References

Jul 7, 1988·Biochimica Et Biophysica Acta·J F Nagle, M C Wiener
Mar 1, 1985·Physical Review A: General Physics·W G Hoover
Apr 23, 1990·Physical Review Letters·E Evans, W Rawicz
Jun 27, 2000·Biophysical Journal·W RawiczE Evans
Nov 7, 2000·Biochimica Et Biophysica Acta·J F Nagle, S Tristram-Nagle
Jun 1, 2001·Physical Review Letters·J B FournierL Peliti
Sep 30, 2004·Biophysical Journal·Jakob Wohlert, Olle Edholm
Oct 8, 2005·Journal of Computational Chemistry·David Van Der SpoelHerman J C Berendsen
May 6, 2006·The Journal of Chemical Physics·Alberto Imparato
May 7, 2009·Chemistry and Physics of Lipids·S Deren GulerStephanie Tristram-Nagle
Aug 27, 2009·The Journal of Physical Chemistry. B·See-Wing ChiuEric Jakobsson

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Citations

Oct 12, 2012·European Biophysics Journal : EBJ·Semen O Yesylevskyy, Alexander P Demchenko
Apr 9, 2013·The Journal of Physical Chemistry. B·Anthony R BraunJohn F Nagle
Sep 22, 2011·The Journal of Chemical Physics·Foram M Thakkar, K G Ayappa
Nov 5, 2013·The Journal of Chemical Physics·Bastien LoubetHimanshu Khandelia
Sep 28, 2010·The Journal of Chemical Physics·Erik G Brandt, Olle Edholm
Jun 14, 2013·The Journal of Chemical Physics·Mingyang HuMarkus Deserno
Sep 25, 2012·The Journal of Chemical Physics·J Stecki
Jan 10, 2012·The Journal of Chemical Physics·Max C WatsonFrank L H Brown
Feb 7, 2016·Biochimica Et Biophysica Acta·David PogerAlan E Mark
Jan 31, 2016·Biochimica Et Biophysica Acta·Marta Pasenkiewicz-GierulaKrzysztof Murzyn
Feb 11, 2016·Biochimica Et Biophysica Acta·Jirasak Wong-Ekkabut, Mikko Karttunen
Jan 26, 2013·Chemistry and Physics of Lipids·Kyu Ii LeeWonpil Im
Apr 4, 2015·The Journal of Chemical Physics·Antonio BenedettoPietro Ballone
May 5, 2011·Biophysical Journal·Erik G BrandtOlle Edholm
May 5, 2011·Biophysical Journal·Anthony R BraunJonathan N Sachs
Jun 9, 2016·Biophysical Journal·Christopher J BarileAndrew A Gewirth
Jul 14, 2016·Journal of Chemical Theory and Computation·Linnea Lundberg, Olle Edholm
Aug 17, 2016·Biochimica Et Biophysica Acta·Yin WangZoe Cournia
Aug 18, 2016·The Journal of Physical Chemistry. B·Jon KaplaArnold Maliniak
Apr 4, 2017·Nature Communications·Matej KandučEmanuel Schneck
Mar 21, 2017·Physical Chemistry Chemical Physics : PCCP·Miguel A GonzalezFernando Bresme
Nov 9, 2017·Physical Biology·N RamakrishnanRavi Radhakrishnan
Nov 28, 2017·Physical Chemistry Chemical Physics : PCCP·Carlos P Herrero, Rafael Ramírez
Aug 3, 2018·The Journal of Chemical Physics·R Ramírez, C P Herrero
Jun 4, 2019·The Journal of Chemical Physics·Carlos P Herrero, Rafael Ramírez
Mar 17, 2018·The Journal of Chemical Physics·Carlos P Herrero, Rafael Ramírez
May 18, 2020·The Journal of Chemical Physics·Sigbjørn Løland BoreMichele Cascella
Feb 6, 2021·Extreme Mechanics Letters·Choon-Peng ChngChangjin Huang
Feb 16, 2021·Journal of the Mechanical Behavior of Biomedical Materials·Ali RasouliHossein Nejat Pishkenari
Jan 21, 2021·Physical Review. E·K R PrathyushaP B Sunil Kumar
Jan 23, 2019·Biophysical Journal·Milka DoktorovaHarel Weinstein
Feb 18, 2020·Chemistry and Physics of Lipids·Drew MarquardtJohn Katsaras
Feb 23, 2012·The Journal of Physical Chemistry. B·Joakim P M Jämbeck, Alexander P Lyubartsev
Aug 22, 2012·The Journal of Physical Chemistry. B·Richard J Bingham, Pietro Ballone
Aug 14, 2012·Journal of Chemical Theory and Computation·Joakim P M Jämbeck, Alexander P Lyubartsev
Mar 17, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Dominik DrabikMarek Langner
Mar 18, 2020·The Journal of Physical Chemistry. B·Behruz BozorgHimanshu Khandelia
Jul 31, 2013·The Journal of Physical Chemistry. B·Navendu BhatnagarJeffrey J Potoff

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