PMID: 6987539Apr 3, 1980Paper

Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae

Nature
J W Szostak, R Wu

Abstract

Unequal sister chromatid exchanges occur at the ribosomal DNA locus of yeast during mitotic growth. The frequency of unequal crossing over, as measured by the deletion or duplication of an inserted genetic marker (LEU2), is sufficient to maintain the sequence homogeneity of the rDNA repeat units.

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Related Concepts

Partial Monosomy
Crossing Over, Genetic
DNA Replication
DNA, Fungal
Cistron
Leucine
Genetic Linkage Analysis
M Phase, Mitotic
Episomes
15S RNA

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