Unequal distribution of cognitive deficits in vascular dementia--is this a valid criterion in the ICD-10?

International Journal of Geriatric Psychiatry
P F BostonC Lamers

Abstract

To investigate the appropriateness of the ICD-10 criterion for vascular dementia which requires unequal distribution of deficits between different domains of cognitive function. Cross-sectional comparative study. Referrals to a specialist memory clinic in Sheffield and a community sample of patients from a general practice population in Melton Mowbray. The CAMCOG part of the Cambridge mental disorders of the elderly examination (CAMDEX) was assessed for 131 Sheffield subjects and 396 Melton Mowbray subjects to examine both total variability and differences between individual subscale items. Depression was also examined as this was a potential confounding factor. After adjustment for age, sex and depression scores, there were no significant differences between vascular dementia subjects and Alzheimer's disease subjects at either centre for total variability of cognitive deficits and little difference between diagnoses for individual subscale items. In Sheffield, subjects with vascular dementia had significantly higher depression scores compared to those with Alzheimer's disease. The usefulness of the concept of unequal deficits as a diagnostic criterion for vascular dementia in routine clinical practice is doubtful.

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Jan 1, 1995·Neuroepidemiology·R Hébert, C Brayne
May 1, 1994·Dementia·T WetterlingK J Borgis
Jan 21, 1993·The New England Journal of Medicine·I SkoogA Svanborg
Jan 1, 1996·Stroke; a Journal of Cerebral Circulation·T WetterlingK J Borgis
Mar 1, 1996·Stroke; a Journal of Cerebral Circulation·S E StarksteinR Leiguarda
Sep 10, 1999·International Journal of Geriatric Psychiatry·P F BostonC Jagger

❮ Previous
Next ❯

Citations

Mar 21, 2002·Epilepsia·Gaetano Zaccara, Cesare Maria Cornaggia
Nov 5, 2004·International Journal of Geriatric Psychiatry·Srinivas SuribhatlaJames Lindesay
Jul 2, 2003·International Journal of Geriatric Psychiatry·Sarah BaillonJames Lindesay
Oct 31, 2015·Neurodegenerative Disease Management·Jennifer G GoldmanCynthia D Schroeder
Oct 1, 2011·Dementia & Neuropsychologia·Eliasz EngelhardtUNKNOWN Working Group on Alzheimer’s Disease and Vascular Dementia of the Brazilian Academy of Neurology

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.