Unexpected complexity of everyday manual behaviors.

Nature Communications
Y. YanSliman J Bensmaia

Abstract

How does the brain control an effector as complex and versatile as the hand? One possibility is that neural control is simplified by limiting the space of hand movements. Indeed, hand kinematics can be largely described within 8 to 10 dimensions. This oft replicated finding has been construed as evidence that hand postures are confined to this subspace. A prediction from this hypothesis is that dimensions outside of this subspace reflect noise. To address this question, we track the hand of human participants as they perform two tasks-grasping and signing in American Sign Language. We apply multiple dimension reduction techniques and replicate the finding that most postural variance falls within a reduced subspace. However, we show that dimensions outside of this subspace are highly structured and task dependent, suggesting they too are under volitional control. We propose that hand control occupies a higher dimensional space than previously considered.

References

Aug 1, 1990·IEEE Transactions on Bio-medical Engineering·S L DelpJ M Rosen
Jan 1, 1989·Journal of Biomechanics·G T Yamaguchi, F E Zajac
Sep 1, 1996·Journal of Biomechanics·P de Leva
May 2, 1998·Journal of Neurophysiology·M Santello, J F Soechting
Dec 23, 2000·Science·J B TenenbaumJ C Langford
Mar 27, 2001·Computer Methods in Biomechanics and Biomedical Engineering·FRANK C. Anderson, MARCUS G. Pandy
Aug 15, 2001·Current Opinion in Neurobiology·K O Johnson
Oct 17, 2001·Journal of Biomechanical Engineering·F C Anderson, M G Pandy
Nov 8, 2001·Journal of Neurophysiology·M H Schieber
Oct 31, 2002·Nature Neuroscience·Emanuel Todorov, Michael I Jordan
Jun 23, 2004·Nature Reviews. Neuroscience·Stephen H Scott
Aug 28, 2004·Nature Neuroscience·Emanuel Todorov
Aug 5, 2005·Annals of Biomedical Engineering·Katherine R S HolzbaurScott L Delp
Nov 9, 2005·Current Opinion in Neurobiology·Tamar Flash, Binyamin Hochner
Nov 15, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Justin C Lee, Jeremiah C Healy
Feb 21, 2006·IEEE Transactions on Bio-medical Engineering·Veronica J Santos, Francisco J Valero-Cuevas
Feb 3, 2007·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·E Todorov, Z Ghahramani
Jun 7, 2007·IEEE Transactions on Bio-medical Engineering·Francisco J Valero-CuevasHood Lipson
Nov 21, 2007·IEEE Transactions on Bio-medical Engineering·Scott L DelpDarryl G Thelen
Jan 25, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Simon A OverduinEmilio Bizzi
Feb 8, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Pramodsingh H ThakurSteven S Hsiao
Mar 11, 2008·Nature Biotechnology·Markus Ringnér
Mar 29, 2008·Experimental Brain Research·James N IngramDaniel M Wolpert
Sep 19, 2008·Journal of Neurophysiology·Jason J KutchWilliam Z Rymer
Jan 14, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jean-Alban Rathelot, Peter L Strick
Apr 17, 2009·Journal of Neurophysiology·Francisco J Valero-CuevasEmanuel Todorov
Oct 16, 2009·Current Opinion in Neurobiology·Matthew C Tresch, Anthony Jarc
Sep 2, 2011·Journal of Neurophysiology·Shinichi FuruyaJohn F Soechting
May 10, 2012·PLoS Computational Biology·Jason J Kutch, Francisco J Valero-Cuevas
Sep 8, 2012·Journal of Neurophysiology·Kornelius RáczFrancisco J Valero-Cuevas
Dec 25, 2012·Neuron·Simon A OverduinEmilio Bizzi
Aug 29, 2014·Nature·Patrick T SadtlerAaron P Batista
Sep 18, 2015·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Simon A OverduinEmilio Bizzi
Jun 9, 2017·Neuron·Juan A GallegoSara A Solla
Mar 14, 2018·Nature Neuroscience·Matthew D GolubByron M Yu
Jun 28, 2019·Nature·Carsen StringerKenneth D Harris

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Citations

Jun 12, 2021·Current Opinion in Neurobiology·Sebastien B HausmannMackenzie W Mathis
Sep 4, 2021·PLoS Computational Biology·Joyneel MisraLuiz Pessoa

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