Unexpected diagnosis for an adrenal tumor: synovial sarcoma

Annals of Diagnostic Pathology
Pierre-Alexandre JustGonzague De Pinieux

Abstract

A 39-year-old woman presented with an incidentally discovered mass of the left adrenal fossa. Computed tomography and magnetic resonance imaging did not show any other lesion. Histologically, this mass was composed of a dense proliferation of spindle cells with a fibrosarcomatous-like pattern. Immunohistochemistry using anticytokeratin showed some epithelial cells within the tumor. The diagnosis of primitive synovial sarcoma of the left adrenal fossa was confirmed by the presence of the characteristic t(X;18) translocation. Despite radiotherapy, several chemotherapies, and 2 other surgical resections, the patient died 30 months after the initial diagnosis. To our knowledge, this report constitutes the first described case of synovial sarcoma arising in the adrenal gland.

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Citations

Oct 4, 2011·Seminars in Ultrasound, CT, and MR·Ling-Ling QiuQin Zhang
Feb 26, 2011·Annales de pathologie·Julie GoninFrédérique Tissier
Dec 15, 2012·Histopathology·Chung-Chieh WangYung-Ming Jeng
Feb 9, 2017·Cancer Control : Journal of the Moffitt Cancer Center·Yi DingMarilyn M Bui

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