Unexpected dramatic increase in CD4+ cell count in a patient with AIDS after enfuvirtide treatment despite persistent viremia and resistance mutations

Journal of Medical Virology
Alessandro SoriaAntonella Castagna

Abstract

An unexpected dramatic immune recovery was observed in a patient with full-blown AIDS receiving enfuvirtide-based antiretroviral therapy after multiple treatment failures. A complex interplay of viral and host factors, including the control of X4 viruses and proviral burden, may favor immune restoration with HIV neutralizing activity, despite persistent viremia.

References

Feb 17, 1997·The Journal of Experimental Medicine·R I ConnorN R Landau
Jan 18, 2003·Blood·Priscilla BiswasAlberto Beretta
Mar 15, 2003·The New England Journal of Medicine·Jacob P LalezariUNKNOWN TORO 1 Study Group
May 30, 2003·The New England Journal of Medicine·Adriano LazzarinUNKNOWN TORO 2 Study Group
Aug 29, 2003·The New England Journal of Medicine·Jody LawrenceUNKNOWN 064 Study Team of the Terry Beirn Community Programs for Clinical Research on AIDS
Feb 1, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Cécile GoujardUNKNOWN Agence Nationale de Recherche sur le Sida PRIMO Study Group
Feb 16, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Francois RaffiMiklos Salgo
Aug 8, 2006·The Journal of Antimicrobial Chemotherapy·Stefano AquaroCarlo Federico Perno
Jan 6, 2007·The Journal of Infectious Diseases·Steven G DeeksDaniel R Kuritzkes

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Citations

Apr 2, 2013·Antiviral Research·Aiman A Haqqani, John C Tilton
Jan 7, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lidia GazzolaGiulia Marchetti
Aug 18, 2009·Antiviral Research·John C Tilton, Robert W Doms
Apr 9, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Francesca CossariniAntonella Castagna

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