Unexpected endometrial malacoplakia related to abortion and placental rests retention: a case report.

Diagnostic Pathology
Antonio d'AmatiLeonardo Resta

Abstract

Malacoplakia is a rare chronic inflammatory disease. The name derives from the Greek "μαλακός" meaning "soft" and "πλάξ" meaning "plaque", describing its usual macroscopic presentation as a friable yellow soft plaque. It was first described by von Hansemann in 1901 and by Michaelis and Gutmann in 1902. The urinary system is the most commonly involved site. Female genital tract involvement is extremely rare. Treatment is prevalently based on antibiotics with surgical intervention sometimes necessary. Prognosis is usually good, but relapse may frequently occur. This report illustrates the first case of endometrial malacoplakia in a 40 years-old patient who received endometrial curettage due to the retention of placental rests following an abortion. After conspicuous vaginal sero-hematic secretions, the patient received a further curettage. The histological examination did not show any retention of chorionic rests, but an endometrial and myometrial infiltration of histiocytes with large granular cytoplasm within a chronic inflammatory background. Immunoreactivity for CK-pool was negative, while CD68 immunostaining was strongly positive. Malacoplakia of endometrium is an extremely rare condition, with few cases reported in the whol...Continue Reading

References

Sep 1, 1985·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S ChadhaF J ten Kate
Oct 15, 1980·American Journal of Obstetrics and Gynecology·A ChalvardjianJ D Cairns
May 28, 2014·Journal of the Neurological Sciences·Hirotaka FudabaMinoru Fujiki

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Citations

Jun 10, 2021·Journal of Surgical Case Reports·María J Irarrázaval-MainguyagueFelipe F Quezada-Diaz

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