Unexpected iron(III) chloride-catalysed dimerisation of 1,1,3-trisubstituted-prop-2-yn-1-ols as an expedient route to highly conjugated indenes

Organic & Biomolecular Chemistry
Weidong Rao, Philip Wai Hong Chan

Abstract

A method to prepare highly conjugated indenes efficiently by iron(III) chloride-catalysed dimerisation of trisubstituted propargylic alcohols under very mild conditions at room temperature is described. The reactions are rapid and operationally straightforward, giving the indene products in good yields and regioselectivity.

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Citations

Aug 31, 2012·Chemistry, an Asian Journal·Yung-Ching WangYi-Hung Liu
Nov 22, 2011·Organic Letters·Yi LuanScott E Schaus

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