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Unexpected limitations in the use of commercial antiglobulin reagents

Transfusion

Jan 1, 1976

Martha L BeckSteven R Pierce

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Abstract

The majority of antiglobulin sera used in blood banks in the USA are commercially prepared immune rabbit sera, designed to be reactive only with human red blood cells sensitized with immunoglobulins or complement components. Current manufacturing methods result in a product that gives r...read more

Mentioned in this Paper

False Positive Reactions
Phosphoglycerate Dehydrogenase Activity
Anti-Antibodies
Anti-Human Globulin Consumption Test
Blood Group Antigens
Direct Coombs Test
Serum
PHGDH gene
Complement component
Coombs Test
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Unexpected limitations in the use of commercial antiglobulin reagents

Transfusion

Jan 1, 1976

Martha L BeckSteven R Pierce

PMID: 1082669

DOI: 10.1046/j.1537-2995.1976.16176130839.x

Abstract

The majority of antiglobulin sera used in blood banks in the USA are commercially prepared immune rabbit sera, designed to be reactive only with human red blood cells sensitized with immunoglobulins or complement components. Current manufacturing methods result in a product that gives r...read more

Mentioned in this Paper

False Positive Reactions
Phosphoglycerate Dehydrogenase Activity
Anti-Antibodies
Anti-Human Globulin Consumption Test
Blood Group Antigens
Paper Details
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