Unexpected roles for core promoter recognition factors in cell-type-specific transcription and gene regulation.

Nature Reviews. Genetics
James A Goodrich, Robert Tjian

Abstract

The eukaryotic core promoter recognition complex was generally thought to play an essential but passive role in the regulation of gene expression. However, recent evidence now indicates that core promoter recognition complexes together with 'non-prototypical' subunits may have a vital regulatory function in driving cell-specific programmes of transcription during development. Furthermore, new roles for components of these complexes have been identified beyond development; for example, in mediating interactions with chromatin and in maintaining active gene expression across cell divisions.

References

May 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·A Ruddell, M Jacobs-Lorena
Aug 28, 1997·Nature·E F MichelottiD Levens
Apr 29, 1999·Proceedings of the National Academy of Sciences of the United States of America·M D RabensteinR Tjian
May 1, 1999·The Journal of Biological Chemistry·E Maldonado
Nov 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·M TeichmannR G Roeder
Apr 24, 2001·Genes & Development·M A HillerM T Fuller
May 16, 2001·Science·D ZhangR G Roeder
Jun 8, 2001·Annual Review of Biochemistry·A M NäärR Tjian
Dec 18, 2001·Nature Cell Biology·Rossitza Christova, Thomas Oelgeschläger
Jan 26, 2002·Molecular Biology of the Cell·Danyang ChenSui Huang
May 30, 2003·Molecular and Cellular Biology·William S MohanLàszlò Tora
Nov 25, 2003·Proceedings of the National Academy of Sciences of the United States of America·Stephan P PersengievMichael R Green
Jul 3, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·Sarah KimminsPaolo Sassone-Corsi
Jul 23, 2004·Molecular Biology of the Cell·Philippe Kieffer-KwonIrwin Davidson
Sep 4, 2004·Proceedings of the National Academy of Sciences of the United States of America·Zainab JallowGert Jan C Veenstra
Mar 19, 2005·Genes & Development·Allison E FalenderJoAnne S Richards
Feb 14, 2006·Proceedings of the National Academy of Sciences of the United States of America·Kenneth G GelesRobert Tjian
Jul 25, 2006·Critical Reviews in Biochemistry and Molecular Biology·Mary C Thomas, Cheng-Ming Chiang
Aug 17, 2006·Nature Reviews. Molecular Cell Biology·Catherine B Millar, Michael Grunstein
Nov 1, 2006·Biochemical Society Transactions·T Juven-GershonJ T Kadonaga
Jan 9, 2007·Developmental Biology·Ekaterina VoroninaRichard N Freiman
Jan 24, 2007·Molecular and Cellular Biology·Yong ChengPeijing Jeremy Wang

❮ Previous
Next ❯

Citations

Apr 28, 2012·Cellular and Molecular Life Sciences : CMLS·Lucy W BarrettSteve D Wilton
Jun 24, 2011·Nature Reviews. Molecular Cell Biology·Jerome JullienJ B Gurdon
Apr 24, 2013·Proceedings of the National Academy of Sciences of the United States of America·Katie L PenningtonMichael T Marr
Oct 2, 2013·Proceedings of the National Academy of Sciences of the United States of America·Haiying ZhouRobert Tjian
Oct 20, 2011·The Journal of Biological Chemistry·Thomas K FelderWolfgang Patsch
Jul 23, 2013·Genes & Development·Wei-Yi ChenRobert G Roeder
Jun 19, 2013·Annual Review of Microbiology·Kimberly B Decker, Deborah M Hinton
Mar 30, 2012·BMC Genomics·Yuanpeng ZhouWeidong Tian
May 17, 2011·Genome Biology·Sean ThomasJohn A Stamatoyannopoulos
Apr 19, 2012·PLoS Genetics·Eavan DorceyChristian S Hardtke
Apr 9, 2014·Cellular and Molecular Neurobiology·Tao DingJian Zhao
Aug 28, 2014·Trends in Cell Biology·Joris van ArensbergenHarmen J Bussemaker
Sep 23, 2014·International Journal of Molecular Sciences·Jekaterina Kazantseva, Kaia Palm
Oct 31, 2015·International Journal of Molecular Sciences·Qianhui WanHuayan Wang
Jan 19, 2016·Trends in Cell Biology·Yan XuMiguel A Esteban
May 11, 2012·Trends in Cell Biology·Yick W FongRobert Tjian
Sep 20, 2011·Trends in Genetics : TIG·Eivind Valen, Albin Sandelin
Jul 12, 2011·Gene·Zhe ZhaoXiaobo Zhang
Jan 1, 2012·Wiley Interdisciplinary Reviews. Developmental Biology·James T Kadonaga
Mar 3, 2015·Stem Cells·Lindsay A LovascoRichard N Freiman
Nov 14, 2012·Biochimie·Maja MalkowskaLucjan Wyrwicz
Mar 8, 2013·Developmental Biology·Bridlin BarckmannRenate Renkawitz-Pohl
Feb 27, 2015·Biomolecular Concepts·Jianbo WangVictor Jin
May 3, 2015·Biochimica Et Biophysica Acta·Yehuda M DaninoTamar Juven-Gershon
May 23, 2014·Current Biology : CB·Maria Vera, Robert H Singer
Apr 1, 2014·Cell·Michael LevineRobert Tjian
Nov 28, 2013·Biochimica Et Biophysica Acta·Ferenc Müller, Làszlò Tora
Nov 12, 2013·Molecular Cell·Yick W FongRobert Tjian

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.