Unfavorable effect of smoking on the elastic properties of the human aorta

Circulation
C StefanadisP Toutouzas

Abstract

Smoking is a major risk factor for cardiovascular morbidity and mortality. Because previous studies have shown that smoking affects vasomotor response, we hypothesized that smoking may also acutely alter aortic elastic properties. We studied 40 male current and long-term smokers who underwent diagnostic cardiac catheterization for chest-pain evaluation. Twenty subjects (age, 48 +/- 2 years, mean +/- SEM) were randomly assigned to smoking and 20 (age, 47 +/- 2 years) to sham smoking studies. Aortic elastic properties were studied with the determination of the aortic pressure-diameter relation before smoking, every minute for the first 5 minutes after the initiation of smoking or sham smoking, and every 5 minutes for the following 15 minutes. Instantaneous diameter of the thoracic aorta was measured with a special ultrasonic dimension catheter developed in our laboratory and previously validated. Instantaneous aortic pressure was measured at the same site as was diameter with a Millar micromanometer. Smoking was associated with significant changes in the aortic pressure-diameter relation that denote deterioration of the elastic properties and were maintained during the whole study period: the slope of the pressure-diameter loop b...Continue Reading

References

Jul 1, 1978·The Journal of Clinical Investigation·D D HeistadF M Abboud
Jan 1, 1990·European Journal of Clinical Pharmacology·I BerlinM Safar
Feb 1, 1989·Journal of the American College of Cardiology·R N IsnardM E Safar
Nov 17, 1988·The New England Journal of Medicine·N L Benowitz
Jan 1, 1988·American Heart Journal·O D Mjøs
May 1, 1986·The American Journal of Cardiology·J E DeanfieldA P Selwyn
Jun 1, 1987·The American Journal of Cardiology·C StefanadisH Boudoulas
Nov 1, 1985·Journal of the American College of Cardiology·T WargovichC R Conti
Feb 11, 1968·The American Journal of Physiology·C W UrschelE Braunwald
Jun 4, 1983·Lancet·J L NadlerR Horton
Feb 1, 1995·Cardiovascular Drugs and Therapy·G G Belz
Dec 1, 1993·Journal of the American College of Cardiology·M J KoolL M Van Bortel
Feb 17, 1994·The New England Journal of Medicine·D J MoliternoL D Hillis
Sep 1, 1993·Journal of the American College of Cardiology·J E QuillenM D Winniford
May 1, 1993·Journal of the American College of Cardiology·H WatanabeY Sugishita
Jan 18, 1996·The New England Journal of Medicine·D S CelermajerJ E Deanfield
May 1, 1962·Circulation Research·J C GREENFIELD, D J PATEL

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Citations

Jan 12, 2000·The International Journal of Angiology : Official Publication of the International College of Angiology, Inc·C StefanadisP Toutouzas
Nov 1, 2006·Irish Journal of Medical Science·Z ZamirJ Feely
Jul 26, 2012·Rheumatology International·Geneviève GygerMurray Baron
Jul 12, 2003·Preventive Medicine·Wendy J MackHoward N Hodis
Feb 17, 2001·Ultrasound in Medicine & Biology·R S Perret, G D Sloop
Apr 10, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Robert J DoonanStella S Daskalopoulou
Jun 28, 2006·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M R Skilton, D S Celermajer
Feb 13, 2007·The Journal of Cardiovascular Nursing·Joaquin Barnoya, Stanton A Glantz
Oct 4, 2006·Journal of the Royal Society, Interface·Ghassan S Kassab
Feb 12, 2009·Clinical and Experimental Pharmacology & Physiology·Dionysios AdamopoulosPhilippe van de Borne
Jan 31, 2009·Journal of Applied Physiology·Marisa Garcia, Ghassan S Kassab
Nov 27, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Irfan BarutcuCevat Kirma
Aug 20, 2011·PloS One·Niema M Pahlevan, Morteza Gharib
Mar 24, 2006·Psychosomatic Medicine·Charalambos VlachopoulosChristodoulos Stefanadis
Sep 28, 2014·Current Treatment Options in Cardiovascular Medicine·Ioana Munteanu, Florin Dumitru Mihălţan
Jan 25, 2003·Coronary Artery Disease·James D CameronBronwyn A Kingwell
Mar 14, 2009·Annals of Biomedical Engineering·Yongsam KimAvner Friedman
Sep 12, 2007·Expert Opinion on Therapeutic Targets·Konstantinos TziomalosDimitri P Mikhailidis
Mar 20, 2004·Expert Review of Cardiovascular Therapy·Azra Mahmud, John Feely
Apr 29, 2015·International Journal of Cardiology·Charalambos VlachopoulosDimitris Tousoulis
Sep 22, 2015·Journal of Clinical Biochemistry and Nutrition·Takeshi OtsukiToshikazu Yoshikawa
Dec 30, 2008·Preventive Medicine·Lorenzo RichiardiFrancesco Barone-Adesi
Oct 24, 2007·Journal of Dermatological Science·Akimichi Morita
Apr 3, 2007·Artificial Intelligence in Medicine·Yüksel OzbayMurat Ceylan
Jan 27, 2007·Atherosclerosis·Mahyar Khaleghi, Iftikhar J Kullo
Dec 2, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Hala Mahfouz Badran, Mohamed Elnoamany
Feb 6, 2004·Experimental Dermatology·Lei YinTakuo Tsuji
Dec 18, 2003·British Journal of Clinical Pharmacology·Azra Mahmud, John Feely
May 30, 1998·The American Journal of Cardiology·J LekakisS Stamatelopoulos
Oct 21, 2015·Journal of the American College of Cardiology·Panagiota PietriChristodoulos Stefanadis
Jul 4, 2006·International Journal of Cardiology·Andreas P MichaelidesChristodoulos I Stefanadis
Dec 5, 1997·The American Journal of Cardiology·J TauthF Matar

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