Unfractionated heparin and mechanical thromboprophylaxis in hip arthroplasty

Acta ortopedica brasileira
Flávio Luís GarciaCelso Hermínio Ferraz Picado

Abstract

To evaluate the efficacy and safety of unfractionated heparin associated with mechanical prophylaxis as a method for preventing venous thromboembolism in hip arthroplasty. We retrospectively reviewed the records of 181 hip arthroplasties out of 216 consecutive cases performed over a period of 39 months in our hospital. We excluded 35 cases due to non-adherence to the standardized method of thromboprophylaxis or loss to follow-up. All arthroplasties evaluated completed one-year follow-up after surgery with five consultations at predefined periods. Efficacy of the proposed method was evaluated by the occurrence of symptomatic venous thromboembolism confirmed by specific tests and safety was determined by the lack of occurrence of major bleeding according to criteria established by the International Society on Thrombosis and Haemostasis. There were four cases of symptomatic venous thromboembolism (2.2%), with three cases of deep vein thrombosis (1.65%) and one case of pulmonary embolism (0.55%). We found one case of severe bleeding (0.55%). Unfractionated heparin associated with mechanical prophylaxis proved to be an effective and safe method for preventing venous thromboembolism in patients undergoing hip arthroplasty, presenting...Continue Reading

References

Jan 1, 1982·The Journal of Bone and Joint Surgery. British Volume·K Hardinge
Jan 21, 2003·The Journal of Bone and Joint Surgery. American Volume·Charlotte B PhillipsJeffrey N Katz
Jun 20, 2003·Circulation·Clive Kearon
Sep 19, 2003·Wiener klinische Wochenschrift·Paul Alexander Kyrle, Sabine Eichinger
May 12, 2005·Thrombosis and Haemostasis·Ola E DahlPaul D Stein
Nov 3, 2009·Journal of Thrombosis and Haemostasis : JTH·S SchulmanUNKNOWN Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on T
Nov 26, 2011·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Sukhdeep K GillJohn P Ivory
Feb 1, 2012·Journal of Thrombosis and Haemostasis : JTH·I TzoranUNKNOWN RIETE Investigators
Feb 22, 2012·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Aswin ChariHemant Pandit
Oct 2, 2012·Lancet·Robert PivecMichael A Mont
Nov 9, 2012·The Journal of Bone and Joint Surgery. British Volume·R L Barrack
Nov 6, 2012·The Journal of Arthroplasty·S M Javad MortazaviJavad Parvizi
Nov 29, 2012·The Journal of Bone and Joint Surgery. British Volume·A B PedersenH T Sørensen
Feb 16, 2013·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Katia SindaliRaj Shrivastava
Aug 21, 2013·Best Practice & Research. Clinical Haematology·Daniel J Quinlan, Bengt I Eriksson
Oct 4, 2013·The Journal of Bone and Joint Surgery. American Volume·Jay R Lieberman, Michael J Pensak
Oct 12, 2013·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Ola E DahlJoakim J Aanesen
May 2, 2014·Osteoarthritis and Cartilage·C Pabinger, A Geissler
Jun 5, 2014·Bone & Joint Research·J R BerstockA W Blom

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Citations

Sep 17, 2017·The International Journal of Lower Extremity Wounds·Valerio ValliniAngelo Bonadio

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Methods Mentioned

BETA
primary hip arthroplasty
total hybrid arthroplasty

Software Mentioned

StatsDirect

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