Unified dosimetry index (UDI): a figure of merit for ranking treatment plans.

Journal of Applied Clinical Medical Physics
Hilary AkpatiAllen Meek

Abstract

We have formulated a unified dosimetry index (UDI) that computes, for any given treatment plan, its deviations in terms of dose coverage, conformity, homogeneity, and dose gradient vis-à-vis an ideal plan (which we define as a dosimetry plan of perfect dose coverage, conformity, homogeneity, and step-wise fall-off to zero dose outside the planning target volume). In order to validate the UDI scoring system, 21 stereotactic cranial radiosurgery cases were evaluated retrospectively. The cases were planned on the BrainSCAN treatment planning system (BrainLAB, Feldkirchen, Germany) using 6 to 8 non-coplanar static beams collimated with the micro multi-leaf collimator (mMLC). We suggest a technique for creating a ranking system that can be utilized for plan evaluation and comparison between multiple plans. Under this system treatment plans are classified as "excellent", "good", "average", or "poor". The proposed ranking system can be utilized as a general guide for generating an optimal dosimetry plan for external beam radiation therapy.

References

Dec 1, 1993·International Journal of Radiation Oncology, Biology, Physics·E ShawL Martin
Feb 1, 1997·International Journal of Radiation Oncology, Biology, Physics·A van't RietW van der Zee
Feb 11, 1998·International Journal of Radiation Oncology, Biology, Physics·D BaltasN Zamboglou
Dec 30, 1998·International Journal of Radiation Oncology, Biology, Physics·T KnöösP Nilsson
Sep 7, 1999·International Journal of Radiation Oncology, Biology, Physics·L H LeungP M Wu
Jul 18, 2000·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·R OozeerF Reboul
Mar 26, 2003·International Journal of Radiation Oncology, Biology, Physics·Nicoletta J Lomax, Stefan G Scheib
Oct 25, 2003·International Journal of Radiation Oncology, Biology, Physics·Thomas H WagnerSanford L Meeks
Apr 28, 2004·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Vincent W C WuJonathan S T Sham
May 28, 2005·Neurosurgery·Steven D ChangJohn R Adler
Jan 18, 2006·International Journal of Radiation Oncology, Biology, Physics·Loïc FeuvretPierre Bey

❮ Previous
Next ❯

Citations

Jan 8, 2013·Journal of Medical Physics·Tejinder KatariaShyam S Bisht
Jun 29, 2014·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Uwe HaverkampHans Theodor Eich
Mar 7, 2014·Bulletin of Mathematical Biology·J C L AlfonsoL Núñez
Oct 5, 2016·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Tiago VenturaLeila Khouri
Dec 14, 2018·Journal of Neurosurgery·Alexis Dimitriadis, Ian Paddick
May 12, 2016·Journal of Applied Clinical Medical Physics·Oliver BlanckAchim Schweikard
Mar 27, 2020·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Ganeshkumar PatelRavindra Shende
Feb 25, 2021·Journal of Applied Clinical Medical Physics·Qi FuJianrong Dai
Feb 24, 2020·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Silvia CalusiLaura Masi

❮ Previous
Next ❯

Software Mentioned

DVH
BrainScan

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.