May 6, 2008

Unilateral cleft lip/palate children: the incidence of type 6 septal deformities in their parents

Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
Ranko MladinaZeljko Orihovac

Abstract

The overall incidence of pathological septal deformity has been found to be significantly higher in unilateral cleft lip/palate (UCLP) children than in control children. Of the seven types of septal deformity according to Mladina's classification, type 6 has been found to be the most frequent in UCLP children, occurring in only 3.7% of the control children. To investigate the incidence of type 6 septal deformity in the parents of UCLP children. UCLP children (N=62) and their parents (N=91) were examined for type 6 septal deformities. Type 6 was found in at least one parent of a UCLP child in 58% of cases. However, it was not found in the parents whose UCLP children did not show a type 6 septal deformity. Type 6 septal deformity is almost a rule in children suffering from UCLP. Type 6 was not seen in the parents whose UCLP children did not show a type 6 septal deformity. There is a morphogenetic predisposition for the development of CLP in children whose parents carry a type 6 septal deformity.

  • References10
  • Citations4

References

Mentioned in this Paper

Family Health Status
Nasal Cavity
Cleft Palate, Isolated
External Nose Structure
Deformity
Cell Septum
Cartilaginous Component
Quantitative Trait, Heritable
Entire Nasal Cavity
Craniometry

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