PMID: 8594537Oct 1, 1995Paper

Unilateral selective brain cooling

Pflügers Archiv : European journal of physiology
G Kuhnen

Abstract

In species with a carotid rete the arterial blood flowing to the brain can be cooled by passing the carotid rete. The mechanism is termed selective brain cooling (SBC). The aim of the study was to evaluate whether SBC could be induced unilaterally. 27 experiments were performed in 2 conscious goats which were prepared with carotid loops to manipulate the blood temperature of the left and right carotid artery independently of each other. The temperature of the left and right hemisphere of the brain was controlled by means of extracorporeal heat exchangers acting on the carotid blood while trunk temperature was clamped at 39.5 degrees C by a heat exchanger in an arteriovenous shunt. Unilateral warming of the brain induced ipsilateral SBC only, and was accompanied by a bilateral increase of the ear skin temperature. The results demonstrate the precise control of brain temperature by SBC since even unilateral temperature deviations of the brain can be reduced by SBC. In conclusion SBC regulates the temperature of single hemispheres rather than the mean brain temperature.

References

May 1, 1975·Journal of Applied Physiology·D J MiletichE T Toyooka
Mar 1, 1991·Pflügers Archiv : European journal of physiology·G Kuhnen, C Jessen
Jan 1, 1974·Reviews of Physiology, Biochemistry and Pharmacology·E Simon

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Citations

Mar 30, 1999·American Journal of Physical Anthropology·I HershkovitzG Leonetti
Sep 5, 2001·American Journal of Human Biology : the Official Journal of the Human Biology Council·Michel Cabanac, Heiner Brinnel
Oct 9, 2002·Medicinal Research Reviews·Guofeng You
Nov 14, 1997·Trends in Pharmacological Sciences·J M NooneyA Feltz
Apr 29, 1998·Trends in Neurosciences·R NobiliJ Ashmore
Oct 27, 2015·American Journal of Physical Anthropology·Gizéh Rangel de LázaroEmiliano Bruner
Mar 5, 2011·Paediatric Anaesthesia·Gianluca BertolizioBruno Bissonnette
May 24, 2011·Medical Hypotheses·Deepak Gupta
Mar 1, 2007·Neurosurgery·Min S ParkKaterina Semendeferi
Oct 31, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Alexandra R Kunz, Charalampos Iliadis

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