PMID: 9557760Apr 29, 1998Paper

Unilateral versus bilateral botulinum toxin injections in adductor spasmodic dysphonia

The Annals of Otology, Rhinology, and Laryngology
T P LangeveldR J Baatenburg de Jong

Abstract

Thyroarytenoid injection of botulinum toxin is the therapy of choice in spasmodic dysphonia. However, there is no convincing evidence as to whether unilateral or bilateral injections are to be preferred. For this reason, a prospective study was designed in which voice quality, duration of effect, and side effects were assessed. Twenty-seven patients with adductor spasmodic dysphonia were treated with percutaneous injections of botulinum toxin. The first treatment consisted of injection of 5 units in the left thyroarytenoid muscle. The second treatment, 2.5 units in both sides, took place when the effect of the first procedure had completely ceased. All patients underwent both procedures. By means of self-rating scales, effects and side effects were assessed over at least 3 months. There was no difference between the procedures in duration of voice improvement, nor in the occurrence of breathy dysphonia. After a bilateral injection, statistically more patients reported swallowing problems. However, most patients preferred the bilateral injection, in spite of more and longer-lasting side effects.

References

Nov 1, 1985·The Annals of Otology, Rhinology, and Laryngology·A BlitzerM E Fink
Sep 1, 1983·The Annals of Otology, Rhinology, and Laryngology·M RosenR R Gacek
Mar 1, 1994·Archives of Otolaryngology--head & Neck Surgery·T MurryG E Woodson
Jan 1, 1993·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·P ZwirnerG E Woodson
Jan 1, 1996·The Annals of Otology, Rhinology, and Laryngology·B J Davidson, C L Ludlow

❮ Previous
Next ❯

Citations

Mar 20, 2002·Current Neurology and Neuroscience Reports·R Tintner, J Jankovic
May 11, 2002·Journal of Voice : Official Journal of the Voice Foundation·Steven BielamowiczAlexis Godlewski
Mar 28, 2006·Journal of Voice : Official Journal of the Voice Foundation·Carolyn R BaylorNicole C Maronian
Nov 3, 2016·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Babette F van EschWilko Grolman
Oct 20, 2001·The Annals of Otology, Rhinology, and Laryngology·T P LangeveldR J Baatenburg de Jong
Jul 24, 2001·The Annals of Otology, Rhinology, and Laryngology·T P LangeveldR J Baatenburg de Jong
Mar 18, 2006·Clinical Rehabilitation·Christopher WattsRenata Whurr
Nov 4, 2017·Toxins·Rachel Kaye, Andrew Blitzer
Nov 9, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Albert L MeratiSteven Belamowicz
Jul 22, 2004·The Cochrane Database of Systematic Reviews·C C W WattsC Nye
Nov 11, 1999·Current Opinion in Neurology·A R Bentivoglio, A Albanese
Apr 16, 2018·Journal of Voice : Official Journal of the Voice Foundation·Anna RumbachDaniel Novakovic

❮ Previous
Next ❯

Related Concepts

Related Feeds

Botulism (ASM)

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.

Botulism

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.