PMID: 2486174Jan 1, 1989Paper

Unilesional mycosis fungoides: clinical, microscopic and immunophenotypic features

The Australasian Journal of Dermatology
G F OliverP M Banks

Abstract

Seven cases are reviewed in which the histologic and immunohistologic features were those of mycosis fungoides, although the patients presented with solitary lesions which did not recur after local therapy (excision in six, radiotherapy in one), with follow-up of 10 months to 18 years. Immunophenotypic staining of paraffin-embedded tissue revealed a predominant T-lymphocyte proliferation in all cases, None of the four cases studied for BER-H2(Ki-1) were positive, in contrast to the "activated" types of spontaneously regressing lymphoid lesion, lymphomatoid papulosis and "Ki-1" lymphoma. Electron microscopy in one case demonstrated the highly convoluted nuclei of the T cells within the infiltrate. These seven cases represent examples of unilesional mycosis fungoides in which the disease has not recurred after therapy, despite features indistinguishable from those of typical generalised mycosis fungoides-type of cutaneous T-cell lymphoma.

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Citations

Jun 18, 2014·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Ercole MazzeoFilippo Bertoni
Nov 19, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·I Amitay-LaishE Hodak
Apr 27, 2012·Journal of the American Academy of Dermatology·Mina S AllyAlistair Robson
Nov 9, 2011·The British Journal of Dermatology·D V ChanK D Cooper
Nov 15, 2017·The American Journal of Dermatopathology·Cynthia M MagroShabnam Momtahen
Apr 7, 2007·The American Journal of Dermatopathology·Sarah N WalshDaniel J Santa Cruz
Jun 16, 2004·Journal of the European Academy of Dermatology and Venereology : JEADV·D V KazakovW Kempf
Oct 6, 2004·Pediatric Dermatology·Qasem A AlsalehEduardo Calonje

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