Unimanual and bimanual intensive training in children with hemiplegic cerebral palsy and persistence in time of hand function improvement: 6-month follow-up results of a multisite clinical trial

Journal of Child Neurology
Ermellina FedrizziGIPCI Study Group

Abstract

This study aims to compare in hemiplegic children the effectiveness of intensive training (unimanual and bimanual) versus standard treatment in improving hand function, assessing the persistence after 6 months. A multicenter, prospective, cluster-randomized controlled clinical trial was designed comparing 2 groups of children with hemiplegic cerebral palsy, treated for 10 weeks (3 h/d 7 d/wk; first with unimanual constraint-induced movement therapy, second with intensive bimanual training) with a standard treatment group. Children were assessed before and after treatment and at 3 and 6 months postintervention using Quality of Upper Extremity Skills Test (QUEST) and Besta Scales. One hundred five children were recruited (39 constraint-induced movement therapy, 33 intensive bimanual training, 33 standard treatment). Constraint-induced movement therapy and intensive bimanual training groups had significantly improved hand function, showing constant increase in time. Grasp improved immediately and significantly with constraint-induced movement therapy, and with bimanual training grasp improved gradually, reaching the same result. In both, spontaneous hand use increased in long-term assessment.

Associated Clinical Trials

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Citations

Feb 26, 2016·Journal of Child and Adolescent Psychopharmacology·Tonya L RichBernadette T Gillick
Oct 7, 2015·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Giovanni BaranelloDaria Riva
Jul 15, 2015·Journal of Physical Therapy Science·Cibele Almeida SantosClaudia Santos Oliveira
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May 14, 2014·Journal of Child Neurology·Leanne SakzewskiAnn-Christin Eliasson
Nov 14, 2015·Neurorehabilitation and Neural Repair·Mitchell SchertzDido Green
Jun 12, 2017·The Cochrane Database of Systematic Reviews·Jennifer M RyanNeil E O'Connell
Apr 2, 2019·The Cochrane Database of Systematic Reviews·Brian J HoareChristine Imms
May 23, 2019·Developmental Medicine and Child Neurology·Arturo NuaraMaddalena Fabbri-Destro

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